Host Protein General Information

  Protein Name
Actin-related protein 2
  Gene Name
ACTR2
  Host Species
Homo sapiens
  Uniprot Entry Name
ARP2_HUMAN
  Protein Families
Actin family
  Subcellular Location
Cytoplasm; cytoskeleton
  External Link
NCBI Gene ID
10097
Uniprot ID
P61160
Ensembl ID
ENSG00000138071
HGNC ID
169
  Related KEGG Pathway
Fc gamma R-mediated phagocytosis hsa04666            Pathway Map 
Bacterial invasion of epithelial cells hsa05100            Pathway Map 
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Shigellosis hsa05131            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Yersinia infection hsa05135            Pathway Map 
Regulation of actin cytoskeleton hsa04810            Pathway Map 
Tight junction hsa04530            Pathway Map 
Endocytosis hsa04144            Pathway Map 
  3D Structure
PDB ID: 6UHC 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -15.99769891 FZR = 1.60959E-54
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.841228125 FZR = 0.001276197
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) Not Specified Virus Region RNA Info RNAantisensepurificationandquantitativemassspectrometry(RAP-MS); Tandemmasstag(TMT)labelling; liquidchromatographycoupledwithtandemmassspectrometry(LC-MS/MS); Westernblot Huh7 cells (liver carcinoma celll ine) . Liver 24h log2 fold change = 8.76745E+13 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ETOPOSIDE . 36462  D0B7EB  DGIdb
ETOPOSIDE . 36462  D0B7EB  .

Protein Sequence Information

MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
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