Host Protein General Information

  Protein Name
PP2A-alpha
  Gene Name
PPP2CA
  Host Species
Homo sapiens
  Uniprot Entry Name
PP2AA_HUMAN
  Protein Families
PPP phosphatase family, PP-1 subfamily
  EC Number
3.1.3.16
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
5515
Uniprot ID
P67775
Ensembl ID
ENSG00000113575
HGNC ID
9299
  Related KEGG Pathway
Chagas disease hsa05142            Pathway Map 
Hepatitis C hsa05160            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Cell cycle hsa04110            Pathway Map 
Oocyte meiosis hsa04114            Pathway Map 
Tight junction hsa04530            Pathway Map 
Adrenergic signaling in cardiomyocytes hsa04261            Pathway Map 
Dopaminergic synapse hsa04728            Pathway Map 
Long-term depression hsa04730            Pathway Map 
Sphingolipid signaling pathway hsa04071            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
AMPK signaling pathway hsa04152            Pathway Map 
TGF-beta signaling pathway hsa04350            Pathway Map 
Hippo signaling pathway hsa04390            Pathway Map 
mRNA surveillance pathway hsa03015            Pathway Map 
Autophagy - other hsa04136            Pathway Map 
Autophagy - animal hsa04140            Pathway Map 
  3D Structure
PDB ID: 2IAE 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -14.6416185 FZR = 1.79066E-45
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -11.44186801 FZR = 3.42E-27

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
LB-100 . 3578572  D02RNR  DGIdb

Protein Sequence Information

MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
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