Host Protein General Information

  Protein Name
Casein kinase II subunit alpha
  Gene Name
CSNK2A1
  Host Species
Homo sapiens
  Uniprot Entry Name
CSK21_HUMAN
  Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily
  EC Number
2.7.11.1
  Subcellular Location
Nucleus
  External Link
NCBI Gene ID
1457
Uniprot ID
P68400
Ensembl ID
ENSG00000101266
HGNC ID
2457
  Related KEGG Pathway
Measles hsa05162            Pathway Map 
PD-L1 expression and PD-1 checkpoint pathway in cancer hsa05235            Pathway Map 
Adherens junction hsa04520            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Prion disease hsa05020            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
NF-kappa B signaling pathway hsa04064            Pathway Map 
Wnt signaling pathway hsa04310            Pathway Map 
Ribosome biogenesis in eukaryotes hsa03008            Pathway Map 
Mitophagy - animal hsa04137            Pathway Map 
  3D Structure
PDB ID: 1JWH 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -7.178959456 FZR = 5.12079E-10
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -8.599815531 FZR = 1.01E-14

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALISERTIB . 24771867  D0S4JK  DGIdb
ALSTERPAULLONE . 5005498  D0H3EV  DGIdb
AZAKENPAULLONE . 6538897  D0DR8N  DGIdb
CHEMBL225519 . 11715767  D03DZO  DGIdb
CYC-116 . 6420138  D0CY1B  DGIdb
fedratinib . 16722836  D0G8BM  DrugCentral
HESPERADIN . 135421442  D05WSM  DGIdb
KENPAULLONE . 3820  D00PWQ  DGIdb
LINIFANIB . 11485656  D0M9QZ  DGIdb
midostaurin . 9829523  D07NVU  DrugCentral
MLN-8054 . 11712649  D0A5MC  DGIdb
nintedanib . 135423438  D09HNV  DrugCentral
PF-00562271 . 11713159  D01SJT  DGIdb
quercetin . 5280343  D0K8KX  DrugCentral
R-406 . 11213558  D0S6TK  DGIdb
ruboxistaurin . 153999  D0W3LI  DrugCentral
ruxolitinib . 25126798  D04LKS  DrugCentral
SB-220025 . 5164  D09ICC  DGIdb
SILMITASERTIB . 24748573  D09JEJ  DGIdb
SP-600125 . 8515  D02PVB  DGIdb
sunitinib . 5329102  D0R0MW  DrugCentral
TOZASERTIB . 5494449  D02XNW  DGIdb

Protein Sequence Information

MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
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