Host Protein General Information

  Protein Name
4-aminobutyrate aminotransferase
  Gene Name
ABAT
  Host Species
Homo sapiens
  Uniprot Entry Name
GABT_HUMAN
  Protein Families
Class-III pyridoxal-phosphate-dependent aminotransferase family
  EC Number
2.6.1.19; 2.6.1.22
  Subcellular Location
Mitochondrion matrix
  External Link
NCBI Gene ID
18
Uniprot ID
P80404
Ensembl ID
ENSG00000183044
HGNC ID
23
  Related KEGG Pathway
Alanine, aspartate and glutamate metabolism hsa00250            Pathway Map 
Valine, leucine and isoleucine degradation hsa00280            Pathway Map 
Propanoate metabolism hsa00640            Pathway Map 
Butanoate metabolism hsa00650            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
beta-Alanine metabolism hsa00410            Pathway Map 
GABAergic synapse hsa04727            Pathway Map 
  3D Structure
AlphaFold ID: P80404 
  2D PNG Download  
  mmCIF File Download   
  PDB File Download   

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 0.780087554 FZR = 1
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.238053301 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
4-HYDROXYBENZALDEHYDE . 126  D00BRD  DGIdb
CHEMBL378577 . 16036927  D0L7RB  DGIdb
CPP-115 . 9794014  D0EJ7U  DGIdb
L-ALANINE . 5950  D09PUL  DGIdb
TIAGABINE . 60648  D0ED7U  DGIdb
VALPROIC ACID . . . DGIdb
VIGABATRIN . 5665  D0R3QY  DGIdb
vigabatrin . 5665  D0R3QY  DrugCentral

Protein Sequence Information

MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
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