Host Protein General Information

  Protein Name
Hydroxymethylglutaryl-CoA synthase
  Gene Name
HMGCS1
  Host Species
Homo sapiens
  Uniprot Entry Name
HMCS1_HUMAN
  Protein Families
Thiolase-like superfamily
  EC Number
2.3.3.10
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
3157
Uniprot ID
Q01581
Ensembl ID
ENSG00000112972
HGNC ID
5007
  Related KEGG Pathway
Valine, leucine and isoleucine degradation hsa00280            Pathway Map 
Butanoate metabolism hsa00650            Pathway Map 
PPAR signaling pathway hsa03320            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Terpenoid backbone biosynthesis hsa00900            Pathway Map 
  3D Structure
PDB ID: 2P8U 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -13.9594281 FZR = 3.1395E-41
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.036153663 FZR = 0.04781448
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .

Protein Sequence Information

MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNIATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
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