Host Protein General Information

  Protein Name
Phospholipase D1
  Gene Name
PLD1
  Host Species
Homo sapiens
  Uniprot Entry Name
PLD1_HUMAN
  Protein Families
Phospholipase D family
  EC Number
3.1.4.4
  Subcellular Location
Cytoplasm; perinuclear region
  External Link
NCBI Gene ID
5337
Uniprot ID
Q13393
Ensembl ID
ENSG00000178209
HGNC ID
9067
  Related KEGG Pathway
Fc gamma R-mediated phagocytosis hsa04666            Pathway Map 
Glycerophospholipid metabolism hsa00564            Pathway Map 
Ether lipid metabolism hsa00565            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Ras signaling pathway hsa04014            Pathway Map 
cAMP signaling pathway hsa04024            Pathway Map 
Sphingolipid signaling pathway hsa04071            Pathway Map 
Phospholipase D signaling pathway hsa04072            Pathway Map 
Endocytosis hsa04144            Pathway Map 
Glutamatergic synapse hsa04724            Pathway Map 
GnRH signaling pathway hsa04912            Pathway Map 
Parathyroid hormone synthesis, secretion and action hsa04928            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Pancreatic cancer hsa05212            Pathway Map 
Choline metabolism in cancer hsa05231            Pathway Map 
  3D Structure
PDB ID: 6U8Z 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info UV cross-linking followed by antisense-mediated affinity purification and mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
AFIMOXIFENE . 449459  D09NST  DGIdb
HALOPEMIDE . 65490  D07RPV  DGIdb
raloxifene . 5035  D01XBA  DrugCentral
TAMOXIFEN . 2733526  D07KSG  DGIdb

Protein Sequence Information

MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSAIYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNCCGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
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