Host Protein General Information

  Protein Name
Gamma-glutamyl hydrolase
  Gene Name
GGH
  Host Species
Homo sapiens
  Uniprot Entry Name
GGH_HUMAN
  Protein Families
Peptidase C26 family
  EC Number
3.4.19.9
  Subcellular Location
Secreted; extracellular space
  External Link
NCBI Gene ID
8836
Uniprot ID
Q92820
Ensembl ID
ENSG00000137563
HGNC ID
4248
  Related KEGG Pathway
Antifolate resistance hsa01523            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Folate biosynthesis hsa00790            Pathway Map 
  3D Structure
PDB ID: 1L9X 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
BEVACIZUMAB . . D04KBL  DGIdb
METHOTREXATE . 126941  D0SV8E  DGIdb
METHYLPHENIDATE . 4158  D02PPN  DGIdb
PEMETREXED . 135410875  D0Y4GO  DGIdb
THIOGUANINE . 2723601  D02ZXM  DGIdb

Protein Sequence Information

MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD
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