Host Protein General Information

  Protein Name
hSIRT3
  Gene Name
SIRT3
  Host Species
Homo sapiens
  Uniprot Entry Name
SIR3_HUMAN
  Protein Families
Sirtuin family, Class I subfamily
  EC Number
2.3.1.286
  Subcellular Location
Mitochondrion matrix
  External Link
NCBI Gene ID
23410
Uniprot ID
Q9NTG7
Ensembl ID
ENSG00000142082
HGNC ID
14931
  Related KEGG Pathway
Central carbon metabolism in cancer hsa05230            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Nicotinate and nicotinamide metabolism hsa00760            Pathway Map 
  3D Structure
PDB ID: 3GLR 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -3.192241261 FZR = 0.494106765
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.651193018 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
NIACINAMIDE . 936  D06NVJ  DGIdb
nicotinamide . 936  D06NVJ  DrugCentral
SURAMIN . 5361  D0H2UB  DGIdb

Protein Sequence Information

MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
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