Virus General Information

  Virus Name
Foot-and-mouth disease virus (FMDV)
  Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Caphthovirinae; Aphthovirus; Foot-and-mouth disease virus
  Virus Molecule Type
ssRNA(+)
  Sequence ID
NC_039210.1
  Genome Type
Non-segmented
  Related Host Erinaceidae Loxodonta africana Sus scrofa Bos taurus Capra hircus Ovis aries Cricetinae Mesocricetus auratus Rattus norvegicus Cavia porcellus
  External Link
 Taxon ID 12110
 Virus-Host DB https://www.genome.jp/virushostdb/view/?mode=view&search_text=Foot-and-mouth+disease+virus

Virus Virion and Genome Information

    Virion Information
Non-enveloped, spherical, about 30 nm in diameter, T=pseudo3 icosahedral capsid surrounding the naked RNA genome. The capsid consists of a densely-packed icosahedral arrangement of 60 protomers, each consisting of 4 polypeptides, VP1, VP2, VP3 and VP4. VP4 is located on the internal side of the capsid
    GENOME Information
Linear ssRNA(+) genome of 7.5-8.5 kb, polyadenylated, composed of a single ORF encoding a polyprotein. Viral genomic RNA has a viral protein (VPg) at its 5'. The long UTR at the 5' end contains an internal ribosome entry site (IRES) type II. The P1 region encodes the structural polypeptides. The P2 and P3 regions encode the nonstructural proteins associated with replication. Encodes a N-terminal leader protease (L protease) in addition to the 3C protease. The shorter 3' UTR is important in (-)strand synthesis.

Virus-RNA -- Host-Protein Interaction

RNA Binding Site RNA Detail Protein Name Host Species Uniprot ID Protein Detail
5'UTR - 3'UTR RNA Info ATP-dependent RNA helicase Mesocricetus auratus A0A1U7R4D1 Pro Info
5'UTR - 3'UTR RNA Info ATP-dependent RNA helicase A Homo sapiens Q08211 Pro Info
5'UTR - 3'UTR RNA Info ATP-dependent RNA helicase A Homo sapiens Q08211 Pro Info
5'UTR - 3'UTR RNA Info Elongation factor 2 Cricetulus griseus P09445 Pro Info
5'UTR - 3'UTR RNA Info Eukaryotic translation initiation factor 4B Mesocricetus auratus A0A3Q0CFL5 Pro Info
5'UTR - 3'UTR RNA Info Gem-associated protein 5 isoform X3 Mesocricetus auratus A0A1U8BHX4 Pro Info
5'UTR - 3'UTR RNA Info Poly(RC)-binding protein 1 Mesocricetus auratus A0A1U7QFH5 Pro Info
5'UTR - 3'UTR RNA Info Poly(RC)-binding protein 2 Mesocricetus auratus A0A3Q0CMK8 Pro Info
5'UTR - IRES RNA Info Polypyrimidine tract-binding protein 1 Homo sapiens P26599 Pro Info
5'UTR - 3'UTR RNA Info Proliferation associated 2G4 Mesocricetus auratus E7CYH3 Pro Info
5'UTR - 3'UTR RNA Info Replication protein A subunit Mesocricetus auratus A0A3Q0CL88 Pro Info
5'UTR - 3'UTR RNA Info RNA helicase Mesocricetus auratus A0A1U8BR45 Pro Info

Virus Sequence Information

>NC_039210.1 Foot-and-mouth disease virus O isolate o6pirbright iso58, complete genome TTGAAAGGGGGCGCTAGGGTTTCACCCCTAGCACGCCAACGACAGTCCCTGCGTTGCACTCCACACTTAC GTTCGCGTGCACGCGGGACCCGATGGACTTTCGTTCACCCACCTACGGTTGGACTCACGGCACCGCGTGG CCATTTTAGCTGGACCGTGTGGACGAACACCGCTTGCGCTTCTCGCGTGACCGGCTAGTACTCTGACCAC TCTCCGCCTACTTGGTCGCTGCGCTGTCTTGGGCACTCCTATTGGGGTCGTTCGACGCTCCACGGGCTCC CCCGTGCGGCGGGCTACGGTGATGGGGCCGTTTCGCGCGGGCTGATCGCCTGGTCTGCTTCGGCTGTCAC CCGAAGCCCGCCTTTCACCCCCCCCCCCCTAAGTTTTACCGTCGTTTCCGACGTAAAGGGGAAGTAACCA CAAGCTTGACACCGCCTGTCCCGGCGTTAAAGGGAAGTAACCACAAGCTTACAACCGCCTACCCCGGTGT TAATGGGATGTAACCACAAGATACACCTTCACCCGGAAGTAAAACGGCAAATTCACACAGTTTTGCCCGT TTTTCATGAGAAACGGGACGTCTGCGCACGAAACGCGCCGTCGCTTGAGGAGGACTTGTACAAACACGAT CTAAACAGGTTTCCCCAACTGACATACACCGTGCAATTTGAAACTCCGCCTGGTCTTTCCAGGTCTAGAG GGGTAACACTTTGTACTGTGCTTGACTCCACGCTCGGTCCACTGGCGAGTGTTAGTAACAGCACTGGTGC TTCGTAGCGGAGCATGGTGGCCGTGGGAACTCCTCCTTGGTAACAAGGACCCACGGGGCCGAAAGCCACG TCCTGACGGACCCACCATGTGTGCAACCCCAGCACGGCAACTTTTCTGTGAAACTCACTCTAAGGTGACA CTGATACTGGTATTCAAGTACTGGTGACAGGCTAAGGATGCCCTTCAGGTACCCCGAGGTAACACGCGAC ACTCGGGATCTGAGAAGGGGACTGGGGCTTCTGTAAAAGCGCCCAGTTTAAAAAGCTTCTATGCCTGGAT AGGTGACCGGAGGCCGGCGCCTTTCCATTATAACTACTGACTTTATGAACACAACTAACTGTTTTATCGC TTTGGTGTACGCTATCAGAGAGATCAGAACGCTTTTCCTTTCACGAGCTACAGGAAAGATGGAATTCACG CTGTACAACGGTGAAAAGAAGACCTTTTACTCCAGGCCCAACAACCACGACAACTGTTGGTTGAACACCA TCCTTCAGTTGTTCAGGTACGTCGATGAGCCTTTCTTCGACTGGGTCTACAACTCACCCCAGAACCTCAC GCTTGAAGCCATCAAACAGCTGGAAGAACTCACAGGGCTTGAGTTACACGAAGGCGGACCGCCTGCCGCT GTTGTTTGGAACATCAAACACTTGCTTCAAACCGGTATTGGTACCGCCTCGCGACCTAGCGAGGTGTGTG TGGTGGACGGTACGAACATGTGTCTGGCTGATTTCCATGCAGGCATCTTCCTGAAAGGACAGGAACATGC CGTGTTTGCTTGTGTCACCTCCAACGGGTGGTACGCGATTGACGATGAGGACTTCTACCCATGGACGCCG GACCCGTCCGACGTTCTGGTGTTCGTTCCATATGATCAAGAACCACTCAACGGAGAATGGAAAATCAACG TTCAGCGGAAGCTCAAGGGAGCTGGACAATCCAGTCCGGCGACCGGCTCGCAGAACCAATCTGGCAATAC TGGCAGCATAATCAACAACTACTACATGCAACAGTACCAGAACTCCATGGACACACAACTTGGTGACAAC GCCATCAGCGGAGGCTCCAACGAGGGCTCCACAGACACAACTTCCAATCACACAACCAACACTCAGAACA ACGACTGGTTTTCCAAGCTCGCAGGTTCTGCCTTCAGCGGTCTTTTTGGCGCCCTTCTTGCTGACAAAAA GACAGAGGAAACCACTCTCCTCGAGGACCGCATCCTCACTACCCGCAACGGACACACGACCTCAACAACA CAGTCGAGTGTCGGAGTCACGTACGGGTATGCAACAGCTGAGGACTTTGTGAGTGGGCCAAACACTTCTG GTCTTGAAACCAGAGTTGTCCAGGCAGAACGCTTCTTCAAAACCCACCTCTTCGATTGGGTCACCAGTGA CCCATTCGGACGCTGCCACCTGTTGGAACTCCCAACTGACCACAAAGGTGTCTACGGAAGTCTGACCGAC TCGTACGCATATATGAGAAACGGTTGGGACGTTGAAGTCACCGCGGTTGGCAACCAGTTCAACGGAGGGT GTCTGTTGGTGGCGATGGTGCCAGAGCTTTGTTCCATCCAGAAGAGGGAGCTGTACCAGCTCACGCTCTT CCCCCATCAGTTCATCAACCCACGCACAAACATGACTGCGCACATCACTGTGCCTTTCGTTGGCGTCAAT CGCTACGACCAGTACAAGGTGCACAAACCTTGGACCCTCGTGGTTATGGTCGTAGCCCCCCTGACTGTCA ACACTGAAGGCGCTCCACAGATCAAGGTGTACGCCAACATTGCCCCAACCAACGTGTACGTAGCGGGCGA GTTTCCTTCCAAAGAGGGAATTTTCCCCGTAGCTTGCAGTGACGGCTATGGTGGCCTGGTGACCACGGAC CCGAAGACGGCTGACCCCGTTTACGGGAAAGTGTTTAACCCCCCACGCAACCTGCTGCCTGGGCGTTTTA CCAATCTCCTTGATGTGGCTGAGGCATGCCCGACGTTTCTGCACTTCGAGGGTGACGTGCCATACGTGAC CACGAAAACAGATTCAGACAGGGTGCTTGCCCAGTTTGACGTGTCCTTAGCAGCAAAGCACATGTCGAAC ACCTTTCTTGCAGGTCTCGCGCAGTACTATGCACAGTACAGTGGCACCATCAACCTGCACTTCATGTTTA CAGGACCCACTGACGCGAAAGCGCGTTACATGGTTGCTTACGCCCCACCGGGCATGGAGCCGCCCCGGAC GCCTGAGGCGGCTGCACACTGCATTCATGCTGAGTGGGACACTGGGCTAAACTCAAAGTTCACTTTCTCC ATCCCCTATCTTTCGGCTGCTGACTACGCATACACCGCGTCAGACGTGGCTGAAACCACGAACGTGCAAG GATGGGTCTGCTTGTTTCAAATCACGCACGGCAAAGCCGACGGCGACGCTTTGGTCGTGTTGGCTAGCGC TGGCAAGGACTTTGAGCTGAGGCTGCCGGTCGACGCCCGCAGAGAAACTACCTCTGCGGGTGAATCAGCA GATCCCGTGACTACCACTGTTGAGAACTACGGTGGTGAGACACAGGTCCAGAGGCGCCAACACACAGACG TCTCGTTCATCATGGACAGATTCGTGAAAGTGACACCGCAAGATCAAATCAACGTTTTGGACCTTATGCA GATCCCTGCCCACACGCTGGTGGGAGCGCTCCTGCGCGCGTCCACTTACTACTTCTCTGACCTGGAGATA GCAGTAAAGCACGAGGGAGACCTCACTTGGGTCCCGAACGGGGCGCCTGAAGCAGCGCTGGAGAACACCA CCAACCCAACAGCTTACCACAAGGCACCACTCACTCGGCTCGCCCTGCCTTACACGGCACCACACCGCGT GTTGGCAACCGTGTATAATGGAGTGTGCAAGTACAGTAAAACTGCTGTGCCCAACGTGAGAGGTGACACC CAGGTGTTGGATCAGAAGGCGTCGCGGGCGCTACCCACCTCCTTCAACTACGGTGCCATCAAAGCAACCC GAGTTAACGAGCTACTTTATCGGATGAAGAGGGCTGAGACATACTGTCCCAGGCCCTTGCTGGCTATCCA TCCAGCCGAAGCCAGACACAAACAGAAAATTGTGGCACCTGTGAAACAGACTTTGAACTTTGACCTTCTC AAGTTGGCTGGAGACGTGGAGTCCAACCCTGGGCCCTTCTTCTTCTCCGACGTCAGGTCAAATTTCTCCA AATTGGTAGAAACCATCAACCAGATGCAGGAGGACATCTCGACAAAACACGGGCCTGACTTTAACCGGTT GGTGTCTGCGTTTGAGGAATTGGCTACTGGAGTGAAAGCAATCAGGACCGGTCTCGACGAGGCCAAACCC TGGTACAAGCTTATTAAGCTCCTAAGCCGCCTGTCGTGTATGGCCGCTGTGGCAGCACGGTCCAAGGACC CAGTCCTTGTGGCCATCATGCTGGCCGACACCGGTCTCGAGATTCTGGACAGCACCTTTGTCGTGAAGAA AATTTCCGATTCGCTCTCCAGTCTCTTTCACGTGCCGGCCCCCGTCTTCAGTTTCGGAGCCCCGATCCTG TTGGCCGGGTTGGTCAAGGTCGCCTCGAGTTTCTTCCGGTCCACACCCGAAGACCTTGAGAGAGCAGAGA AACAGCTCAAAGCACGTGACATTAACGACATTTTCGCCGTTCTCAAGAACGGCGAGTGGCTGGTCAAGTT GATCCTTGCCATCCGCGACTGGATTAAGGCATGGATCGCCTCAGAGGAGAAGTTCGTCACCATGACAGAC CTGGTGCCTGGTATCCTTGAAAAGCAGCGGGACCTCAACGACCCAAGCAAGTACAAGGAAGCCAAGGAGT GGCTCGACAACGCGCGCCAAGCGTGTTTGAAGAACGGGAACGTCCACATCGCTAACCTGTGCAAAGTGGT CGCCCCAGCACCCAGCGAGTCGAGACCCGAACCCGTGGTCGTTTGCCTCCGTGGCAAGTCCGGCCAGGGC AAGAGTTTCCTTGCGAACGTGCTCGCGCAAGCAATCTCCACTCACTTTACTGGTAGAACCAATTCCGTTT GGTACTGCCCACCTGACCCTGACCACTTCGACGGCTACAACCAGCAGACCGTTGTAGTGATGGATGACCT GGGTCAGAACCCCGATGGCAAGGACTTCAAGTACTTCGCCCAAATGGTTTCAACCACGGGGTTCATCCCG CCCATGGCGTCACTCGAGGACAAAGGCAAACCTTTCAACAGCAAGGTCATCATCGCAACCACCAACCTGT ACTCGGGTTTTACCCCGAAGACTATGGTGTGCCCTGATGCGCTGAACCGGAGGTTCCACTTTGACATCGA CGTGAGCGCCAAGGACGGGTACAAAATTAACAACAAACTGGACATCGTCAAAGCACTTGAAGACACTCAC ACCAACCCGGTAGCAATGTTTCAGTACGACTGTGCCCTTCTCAACGGCACGGCCGTTGAAATGAAGAGAA TGCAGCAGGACTTGTTCAAGCCTCAACCACCCCTCCAGAACGTGTACCAGCTCGTTCAGGAGGTGATTGA ACGGGTCGAGCTCCACGAGAAAGTGTCGAGCCACCCGATTTTCAAGCAGATCTCAATTCCTTCCCAAAAA TCCGTGTTGTACTTCCTCATTGAGAAAGGTCAACACGAGGCGGCAATTGAATTCTTTGAGGGCATGGTGC ACGACTCCATCAAGGAGGAGCTCCGACCCCTCATCCAACGAACCTCATTTGTGAAACGCGCTTTTAAGCG TCTGAAGGAAAACTTTGAGACTGTTGCCCTGTGCTTGACCCTCTTGGCCAACATAGTGATCATGATCCGT GAAACCCACAAGAGGCAGAAGATGGTGGATGGCTCGGTGAATGAGCACATCGAGAAGGCAAACAACACCG CAGACGATGAAACTCTTGACGAGGCGGGAAAGAACCCTCTGGAAACCAGTGGTGCCAGCACCGTTGGCTT CAGAGAGAGAACTCTCACGGACCGAAAGGCGCGTGATGACGTGGGCTTCGAGCCCGCATATCCTGCTGAA GAGTACCCACAAGCTGAAGGACCCTACGCCGGGCCACTCGAGCGTCAGAGACCTCTGAAAGTGAGAGCCA AGCTCCCACAACAGGAGGGACCCTACGCTGGTCCGATGGAGAGACAGAAACCACTGAAAGTGAAAGTGAA AAACCCGGTCATTAAGGAAGGACCCTACGAAGGACCGGTGAAGAAGCCTGTCGCTTTGAAAGTGAAAGCC AAGAACTTAATTGTCACTGAGAGTGGTGCCCCACCGACCGACTTGCAAAAGATGGTCATGGGCAACACAA AGCCTGTTGAGCTTATCCTTGACGGGAAGACAGTAGCCATCTGCTGTGCTACTGGAGTGTTTGGTACTGC TTACCTCGTGCCTCGTCACCTTTTTGCAGAGAAGTATGACAAAATCATGTTGGACGGCAGAGCCATGACA GACAGTGACTACAGAGTGTTTGAGTTTGAGATTAAAGTAAAAGGACAGGACATGCTCTCGGACGCCGCAC TCATGGTACTCCACCGCGGGAACCGTGTGAGAGACATCACGAAACACTTTCGTGATACAGCAAGAATGAA GAAAGGCACTCCCGTTGTTGGTGTGATCAACAACGCAGACGTCGGGAGGCTGATTTTCTCTGGTGAGGCC CTCACCTACAAGGATATCGTAGTGTGCATGGATGGAGATACCATGCCTGGCCTTTTTGCCTATAAGGCCG CCACCAAGGCCGGTTACTGTGGAGGAGCCGTTCTCGCTAAGGACGGGGCTGACACGTTCATCGTCGGCAC TCACTCTGCAGGAGGCAATGGAGTAGGATACTGTTCGTGTGTTTCCAGGTCCATGCTTCAAAAGATGAAG GCACACATTGACCCCGAACCACACCACGAGGGTTTGGTTGTCAACACCAGAGATGTGGAAGAGCGCGTTC ACGTGATGCGCAAAACCAAGCTTGCACCCACCGTTGCACACGGTGTGTTCAACCCTGACTTTGGGCCTGC CGCCTTGTCTAACAAGGACCCGCGCCTGAACGAGGGTGTTGTCCTCGATGAAGCCATCTTCTCCAAACAC AAGGGAGACACAAAGATGTCCGAGGAAGACAAAGCGCTGTTCCGCCGTTGTGCTGCTGACTACGCCTCAC GCTTGCACAGCGTACTGGGTACAGCAAATGCCCCATTGAGCATCTACGAGGCAATCAAGGGCGTTGATGG ACTCGACGCCATGGAGCCAGACACTGCGCCTGGCCTCCCCTGGGCACTCCAGGGGAAACGTCGTGGCGCG CTCATCGATTTTGAGAACGGCACGGTCGGGCCCGAAGTCGAGGCTGCCTTGAAGCTCATGGAGAGAAGAG AATACAAATTTGTTTGCCAGACCTTCCTGAAGGACGAAATTCGCCCGATGGAGAAAGTACGTGCCGGCAA GACTCGCATTGTCGACGTTTTGCCCGTTGAACACATTCTTTACACCAGGATGATGATTGGCAGATTCTGT GCACAAATGCACTCAAACAACGGACCGCAAATTGGCTCAGCAGTCGGTTGTAACCCTGATGTTGATTGGC AAAGATTTGGCACACACTTCGCCCAATACAGAAACGTGTGGGACGTGGACTACTCGGCCTTCGATGCTAA CCACTGCAGTGACGCAATGAACATCATGTTTGAGGAAGTGTTCCGCACGGACTTTGGTTTTCACCCAAAT GCTGAGTGGATCCTGAAGACTCTCGTGAACACGGAACACGCCTATGAAAATAAACGTATCACTGTCGAGG GCGGGATGCCATCTGGTTGTTCCGCAACAAGCATCATCAACACAATCTTGAACAACATATATGTGCTCTA CGCCTTGCGTAGACACTATGAGGGAGTTGAGCTGGATACTTACACCATGATCTCATACGGAGACGACATC GTGGTGGCAAGTGACTACGATTTGGACTTTGAGGCTCTCAAGCCCCACTTTAAATCTCTCGGTCAAACCA TTACTCCAGCTGACAAAAGCGACAAAGGTTTTGTTCTCGGACATTCCATCACCGATGTCACTTTCCTCAA AAGACACTTCCACATGGATTATGGAACTGGGTTTTACAAACCTGTGATGGCCTCAAAGACTCTCGAGGCC ATTCTCTCCTTTGCACGCCGTGGGACCATACAGGAGAAGTTGATCTCCGTGGCAGGACTCGCCGTCCACT CCGGACCAGACGAGTACCGGCGTCTCTTTGAACCCTTCCAGGGCCTCTTTGAGATTCCAAGCTACAGATC ACTTTACCTGCGTTGGGTGAACGCCGTGTGCGGTGACGCATAATCCCTCAGAGATCACAATTGGCACAAT GACTCTGGGGCGCGCGACGCCGTAGGAGTGAAAAGCCCGAAGGGCTTCTCCCGCTTCCTTATCCCAAAAA AAAAAAAAAAA
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