Virus General Information

  Virus Name
Enterovirus 71 (EV71)
  Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Ensavirinae; Enterovirus; Enterovirus A
  Virus Molecule Type
ssRNA(+)
  Sequence ID
U22521.1
  Genome Type
Non-segmented
  Related Host Homo sapiens
  Related Disease Hand, foot and mouth disease Enterovirus infection
  External Link
 Taxon ID 39054
 Virus-Host DB https://www.genome.jp/virushostdb/39054
 KEGG GENOME ID T40343

Virus Virion and Genome Information

    Virion Information
Non-enveloped, spherical, about 30 nm in diameter, T=pseudo3 icosahedral capsid surrounding the naked RNA genome. The capsid consists of a densely-packed icosahedral arrangement of 60 protomers, each consisting of 4 polypeptides, VP1, VP2, VP3 and VP4. VP4 is located on the internal side of the capsid.
    GENOME Information
Monopartite, linear ssRNA(+) genome of 7.2-8.5 kb, polyadenylated, composed of a single ORF encoding a polyprotein. Viral genomic RNA has a viral protein (VPg) at its 5' end instead of a methylated nucleotide cap structure. The long UTR at the 5' end contains a type I internal ribosome entry site (IRES). The P1 region encodes the structural polypeptides. The P2 and P3 regions encode the nonstructural proteins associated with replication.

Virus-RNA -- Host-Protein Interaction

RNA Binding Site RNA Detail Protein Name Host Species Uniprot ID Protein Detail
5'UTR RNA Info Heterogeneous nuclear ribonucleoprotein A1 Homo sapiens P09651 Pro Info

Virus-RNA -- Host-ncRNA Interaction

RNA Binding Site RNA Detail HncRNA Name Host Species External Link HncRNA Detail
VP1 RNA Info hsa-miR-296-5p Homo sapiens miRBase HncRNA Info
VP3 RNA Info hsa-miR-296-5p Homo sapiens miRBase HncRNA Info
VP1 RNA Info hsa-miR-590-5p Homo sapiens miRBase HncRNA Info

Virus Sequence Information

>U22521.1 Human enterovirus 71 polyprotein gene, complete cds TTAAAACAGCTGTGGGTTGTCACCCACCCACAGGGTCCACTGGGCGCTAGTACACTGGTATCTCGGTACC TTTGTACGCCTGTTTTATACCCCCTCCCTGATTTGCAACTTAGAAGCAACGCAAACCAGATCAATAGTAG GTGTGACATACCAGTCGCATCTTGATCAAGCACTTCTGTATCCCCGGACCGAGTATCAATAGACTGTGCA CACGGTTGAAGGAGAAAACGTCCGTTACCCGGCTAACTACTTCGAGAAGCCTAGTAACGCCATTGAAGTT GCAGAGTGTTTCGCTCAGCACTCCCCCCGTGTAGATCAGGTCGATGAGTCACCGCATTCCCCACGGGCGA CCGTGGCGGTGGCTGCGTTGGCGGCCTGCCTATGGGGTAACCCATAGGACGCTCTAATACGGACATGGCG TGAAGAGTCTATTGAGCTAGTTAGTAGTCCTCCGGCCCCTGAATGCGGCTAATCCTAACTGCGGAGCACA TACCCTTAATCCAAAGGGCAGTGTGTCGTAACGGGCAACTCTGCAGCGGAACCGACTACTTTGGGTGTCC GTGTTTCTTTTTATTCTTGTATTGGCTGCTTATGGTGACAATTAAAGAATTGTTACCATATAGCTATTGG ATTGGCCATCCAGTGTCAAACAGAGCTATTGTATATCTCTTTGTTGGATTCACACCTCTCACTCTTGAAA CGTTACACACCCTCAATTACATTATACTGCTGAACACGAAGCGATGGGCTCCCAGGTCTCCACACAGCGA TCCGGCTCGCATGAGAATTCCAACTCAGCCACGGAAGGCTCCACTATAAATTACACAACCATTAATTACT ACAAAGACTCGTATGCTGCCACTGCTGGAAAGCAAAGTCTCAAACAAGATCCTGACAAGTTTGCGAACCC TGTGAAGGACATCTTTACTGAAATGGCAGCGCCCTTAAAGTCTCCCTCTGCTGAAGCATGTGGCTATAGC GACCGAGTGGCACAGCTTACCATTGGAAATTCCACCATTACTACACAAGAAGCAGCAAACATAATAGTTG GGTATGGTGAGTGGCCTTCATACTGCTCTGATAATGATGCAACAGCGGTAGACAAACCTACACGGCCTGA TGTCTCAGTAAATAGATTTTACACGCTAGACACTAAGCTATGGGAGAAATCATCCAAGGGGTGGTACTGG AAGTTCCCAGATGTACTGACTGAAACCGGAGTTTTTGGTCCAAATGCACAATTTCACTACTTATACCGTT CAGGGTTCTGCATCCACGTTCAATGTAACGCTAGCAAATTTCACCAAGGGGCGCTACTCGTTGCGGTATT GCCCGAGTATGTCATTGGAACAGTGGCAGGCGGCACAGGCACAGAGAACAGTCACCCTCCTTATAAACAA ACCCAACCCGGCGCTGATGGATTTGAATTACAACATCCATATGTTCTTGATGCTGGAATTCCAATATCTC AGTTGACAGTGTGCCCTCACCAGTGGATCAATTTACGAACCAACAATTGTGCCACCATAATAGTGCCATA CATGAACACACTACCTTTTGATTCCGCATTGAACCACTGTAATTTCGGACTATTGGTGGTGCCTATCAGC CCGCTGGATTTCGACCAAGGGGCGACACCGGTAATTCCTATCACTATCACGTTGGCTCCGATGTGTTCTG AGTTTGCGGGTCTCAGGCAGGCAGTTACGCAGGGTTTTCCCACTGAATTGAAACCTGGCACTAATCAGTT CTTAACCACGGATGATGGTGTGTCAGCACCTATATTGCCAAATTTCCACCCCACCCCGTGCATTCACATA CCTGGCGAGGTTAGAAACTTACTAGAACTGTGCCAGGTAGAAACCATTTTAGAAGTCAACAATGTGCCCA CCAACGCAACCAGTTTGATGGAAAGGCTACGGTTTCCAGTGTCAGCCCAAGCAGGGAAAGGTGAGTTGTG TGCAGTGTTCAGGGCCGACCCTGGGAGGGATGGTCCTTGGCAATCCACCATGCTAGGCCAGTTGTGTGGA TATTACACCCAATGGTCAGGGTCTTTGGAAGTCACTTTTATGTTCACCGGATCCTTTATGGCAACTGGTA AAATGCTTATAGCTTACACACCCCCAGGGGGCCCTTTGCCTAAAGATAGAGCCACAGCTATGCTGGGGAC GCACGTCATCTGGGACTTTGGCTTGCAATCGTCCGTCACCCTCGTCATACCATGGATCAGTAACACTCAC TATAGGGCGCATGCTCGAGATGGGGTGTTTGATTACTACACCACAGGTTTGGTTAGTATATGGTACCAAA CAAATTATGTAGTCCCTATTGGAGCACCTAATACTGCCTATATAATAGCGTTGGCAGCAGCCCAAAAGAA TTTCACTATGAAATTGTGCAAGGACACCAGTGACATTTTGGAAACGGCCACTATTCAAGGGGACAGAGTG GCAGATGTGATTGAGAGCTCTATAGGAGATAGTGTGAGTAAGGCCCTCACCCCAGCTTTACCTGCACCCA CAGGCCCAGACACCCAAGTGAGCAGTCATCGCTTAGACACTGGAAAAGTACCAGCACTTCAAGCCGCCGA AATCGGAGCTTCGTCGAATGCTAGTGATGAGAGTATGATTGAGACTCGGTGTGTTCTTAACTCACATAGC ACAGCTGAAACCACCCTTGATAGTTTCTTCAGCAGAGCAGGCTTAGTTGGGGAGATAGATCTTCCTCTAA AGGGCACCACCAATCCGAACGGGTATGCCAACTGGGACATAGACATAACCGGTTATGCGCAGATGCGCAG AAAAGTGGAACTATTCACCTATATGCGCTTTGACGCAGAGTTCACTTTTGTCGCGTGCACACCTACCGGA AGGGTCGTTCCACAGCTGCTTCAATACATGTTTGTTCCACCCGGGGCCCCCAAACCAGACTCCAGAGACT CTTTGGCTTGGCCAACGGCCACGAACCCCTCAGTTTTTGTCAAATCATCCGACCCACCAGCACAAGTCTC AGTGCCATTTATGTCACCTGCAAGCGCATACCAATGGTTTTATGACGGATACCCTACATTTGGAGAGCAC AAGCAAGAGAAGGATCTCGAGTATGGGGCATGCCCGAATAACATGATGGGCACATTCTCAGTGCGGACTG TGGGATCGTCAAAGTCAGAATATTCCTTAGTCATCAGAATATACATGAGAATGAAGCACGTCAGAGCGTG GATACCTCGGCCGATGCGCAATCAGAACTATTTGTTCAAATCCAACCCAAACTATGCTGGTGATTCCATT AAACCAACTGGTACCAGCCGAACGGCAATCACTACGCTCGGGAAATTCGGTCAGCAGTCTGGGGCTATTT ATGTGGGCAACTTTAGGGTAGTAAACAGACACCTAGCCACCCATACTGACTGGGCCAACTTGGTGTGGGA AGACAGCTCTAGAGACCTCCTAGTTTCTTCAACTACCGCTCAAGGGTGTGACACCATTGCTCGATGTAAC TGCCAAACCGGAGTGTATTACTGTAACTCTCGCAGAAAACACTATCCAGTCAGTTTTTCGAAACCTAGTT TGGTGTTTGTAGAAGCTAGTGAGTATTATCCAGCTAGATATCAGTCCCATCTTATGCTTGCTGAGGGCCA TTCAGAACCTGGTGATTGTGGCGGTATTCTTAGATGCCAACACGGTGTGGTGGGAATTGTCTCCACTGGC GGAAGTGGCCTTGTGGGATTTGCTGACGTTAGAGATCTTCTGTGGCTAGATGAGGAAGCGATGGAGCAGG GGGTATCTGATTACATCAAAGGTCTCGGTCGAGCCTTCGGCACAGGTTTCACTGACGCAGTGTCTAGGGA AGTGGAAGCGTTGAAGAACCACTTAATCGGCTCCGAAGGGGCTGTTGAGAAGATCTTGAAGAACTTGGTG AAGCTAATTTCAGCCTTAGTTATAGTCATCAGAAGTGATTATGATATGGTCACCCTCACAGCCACACTAG CTCTGATCGGGTGCCACGGGAGTCCTTGGGCGTGGATCAAATCAAAGACAGCTTCCATACTGGGCATTCC CATGGCACAAAAACAGAGTGCCTCATGGCTAAAGAAGTTCAATGACATGGCAAATGCTGCAAAAGGGCTT GAGTGGATTTTCAACAAGATCAGTAAGTTCATTGACTGGCTTAAAGAGAAGATCATTCCAGCTGCCAAAG AGAAAGTTGAGTTTTTGAACAACCTAAAACAGCTCCCCTTGTTGGAGAACCAAGTCTCCAATCTTGAACA GTCTGCTGCCTCACAAGAAGACTTAGAAGCTATGTTTGGTAATGTGATATATCTGGCTCACTTTTGCCGC AAATTCCAACCACTCTACGCAACTGAGGCCAAGAGAGTCTACGCTTTAGAGAAAAGGATGAATAACTACA TGCAGTTCAAGAGCAAACACCGTATTGAACCTGTATGCTTGATCATCAGAGGTTCCCCCGGAACGGGCAA ATCGCTCGCCACAGGCATTATAGCTAGAGCCATTGCTGACAAGTATCGCTCTAGTGTATACTCACTCCCC CCAGACCCAGATCACTTTGATGGGTATAAGCAACAGGTGGTCGCGGTCATGGATGATCTCTGCCAGAACC CGGACGGAAAAGACATGTCCCTATTTTGTCAAATGGTTTCTACAGTAGATTTTGTACCACCCATGGCATC ACTAGAGGAGAAAGGAGTGTCCTTCACCTCTAAGTTTGTCATTGCATCGACCAATGCTAGTAACATCATA GTCCCCACAGTTTCAGATTCAGATGCAATTCGCAGGCGATTCTATATGGACTGCGATATAGAAGTGACAG ATTCTTACAAGACAGACCTCGGTCGGCTGGACGCAGGTAGAGCTGCCAAGCTTTGTACAGAAAATAACAC TGCTAATTTTAAGAGATGCAGCCCACTGGTGTGTGGTAAGGCTATTCAGCTGAGAGACAGGAAGTCCAAA GTGAGATATAGCGTCGACACCGTGGTATCGGAACTGATCAGAGAGTACAACAATAGATCTGCTATTGGGA ATACTATAGAAGCACTCTTTCAAGGACCCCCTAAATTCAGGCCTATAAGAATTAGTCTCGAAGAAAAGCC AGCCCCAGATGCCATTAGCGATCTCCTCGCTAGTGTAGATAGCGAGGAGGTGCGTCAGTACTGCAGGGAA CAAGGCTGGATCATCCCTGAAACTCCCACCAATGTTGAGCGTCACCTCAATAGAGCAGTATTGGTAATGC AGTCCATCGCCACTGTGGTTGCAGTTGTGTCTCTTGTTTATGTCATTTATAAGCTGTTTGCCGGGTTCCA GGGTGCTTACTCTGGAGCGCCCAAGCCCATTCTCAAGAAGCCCGTGTTAAGAACAGCCACGGTCCAAGGG CCCAGCTTAGACTTCGCCTTGTCTCTTTTGAGGCGCAACATTAGACAAGCGCAAACTGACCAAGGACACT TCACCATGCTAGGAGTGCGAGATCGCCTAGCCATCCTGCCGCGCCACTCGCAACCAGGGAAGACCATCTG GGTAGAGCATAAATTAATCAATGTACTAGATGCAGTTGAGTTGGTGGATGAGCAAGGTGTAAACTTGGAA CTCACACTGGTAACTTTGGACACCAATGAAAAATTTAGGGATATCACCAAGTGTATCCCAGAAGTGATCA CCGGGGCGAGTGACGCAACTCTAGTCATCAACACTGAGCACATTCCCTCAATGTTTGTGCCGGTGGGTGA CGTTGTGCAGTACGGTTTCTTGAACCTTAGTGGTAAACCCACACACAGAACCATGATGTATAACTTCCCC ACGAAGCCAGGACAGTGTGGGGGGGTGGTTACCTCAGTTGGTAAGATCATTGGAATCCACATTGGCGGGA ATGGACGCCAGGCCTTTTGCGCTGGCCTAAAGAGGAGTTATTTTGCCAGCGAGCAAGGAGAGATCCAGTG GATGAAGCCTAACAGAGAAACCGGGAGGTTGAATATTAATGGTCCAACCCGAACTAAGCTGGAACCCAGT GTATTCCATGATGTGTTCGAGGGCAACAAGGAACCAGCGGTCCTGACTAGTAAGGACCCCAGACTTGAGG TTGATTTTGAGCAAGCTTTGTTCTCCAAGTATGTGGGTAACACCCTGCATGAACCTGATGAGTACGTGAC ACAGGCTGCTCTCCACTACGCAAATCAGCTGAAGCAACTGGACATCAACACCAGCAAGATGAGCATGGAA GAAGCGTGCTATGGCACAGAATATTTAGAAGCTATAGACTTGCACACCAGTGCTGGATACCCTTATAGTG CTTTGGGCATCAAGAAAAGAGACATCCTCGACCCAGTTACCAGAGACACCTCCAGGATGAAGTTATATAT GGATAAGTATGGGTTGGACTTGCCTAATTCCACTTATGTAAAGGATGAGCTTAGTTCTCTAGATAAGATC AGAAAAGGGGAGTCTCGCCTGATTGAGGCTAGCAGCTTAAATGATCCTGTCTACCCTAGATTGACTTTTG GACACCTTTATGAAGTGTTTCACGCCAACCCAGGGACTGTAACAGGATCTGCAGTTGGGTGCAACCCTGA TGTATTTTGGAGCAAGTTACCAATTTTGTTACCGGGTTCACTCTTTGCATTTGACTACTCAGGATATGAT GCAAGCCTTAGTCCTGTGTGGTTCAGAGCTCTAGAGTTGGTTCTGAGAGAGATCGGTTACTCGGAGGAGG CTGTGTCACTCATAGAAGGGATCAATCACACCCACCACGTGTACCGAAACAAGACATATTGTGTACTTGG TGGAATGCCCTCAGGCTGCTCCGGTACTTCCATTTTCAATTCCATGATTAACAACATAATCATCAGAACC CTCCTGATTAAAACATTCAAAGGTATAGACTTAGATGAGCTGAAAATGGTAGCTTATGGAGATGACGTGT TGGCCAGCTACCCGTTTCCTATTGATTGCTTGGAATGGGGTAAAACAGGCAAAGAATATGGGCTGACTAT GACTCCTGCTGATAAATCACCTTGTTTCAATGAGGTTACCTGGGAGAATGCAACCTTCTTAAAACGGGGT TTTCTACCGGACCATCAGTTCCCTTTTCTGATCCATCCCACTATGCCCATGAGGGAAATCCATGAGTCCA TCCGCTGGACCAAGGACGCGCGCAATACTCAAGATCATGTGCGCTCCCTTTGTCTCCTGGCATGGCATAA TGGAAAAGAGGAGTATGAGAAATTTGTGAGTACAATTAGATCAGTCCCCATTGGAAGGGCTTTAGCAATT CCAAATTTGGAGAACTTGAGAAGAAATTGGCTCGAGTTATTTTAAACTTACAGCTCAATGCTGAACCCCA CCAGAAATCTGGTCGTGTCAATGACTGGTGGGGGTAAATTTGTTATAACCAGAATAGC
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