Host Protein General Information

  Protein Name
Cathepsin B
  Gene Name
CTSB
  Host Species
Homo sapiens
  Uniprot Entry Name
CATB_HUMAN
  Protein Families
Peptidase C1 family
  EC Number
3.4.22.1
  Subcellular Location
Lysosome
  External Link
NCBI Gene ID
1508
Uniprot ID
P07858
Ensembl ID
ENSG00000186522
HGNC ID
2527
  Related KEGG Pathway
Antigen processing and presentation hsa04612            Pathway Map 
NOD-like receptor signaling pathway hsa04621            Pathway Map 
Autophagy - animal hsa04140            Pathway Map 
Lysosome hsa04142            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Renin secretion hsa04924            Pathway Map 
  3D Structure
PDB ID: 1CSB 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Sindbis virus 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Ebola virus (strain VeroVP30) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver . MIST = 0.68552078 .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .
Sindbis virus (strain Toto1101) 5'UTR - 3'UTR RNA Info Cross-link-assisted mRNP purification (CLAMP) and UV cross-linking and immunoprecipitation sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
boceprevir . 10324367  D0V3YT  DrugCentral
BORTEZOMIB . 387447  D0SH3I  DGIdb
carfilzomib . 11556711  D00UVA  DrugCentral
COUMARIN . 323  D03ZMQ  DGIdb
nitroxoline . . . DrugCentral
telaprevir . 3010818  D0X9CH  DrugCentral
UREA . 1176  D02XBW  DGIdb

Protein Sequence Information

MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
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