Host Protein General Information

  Protein Name
Glutathione reductase
  Gene Name
GSR
  Host Species
Homo sapiens
  Uniprot Entry Name
GSHR_HUMAN
  Protein Families
Class-I pyridine nucleotide-disulfide oxidoreductase family
  EC Number
1.8.1.7
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
2936
Uniprot ID
P00390
Ensembl ID
ENSG00000104687
HGNC ID
4623
  Related KEGG Pathway
Diabetic cardiomyopathy hsa05415            Pathway Map 
Thyroid hormone synthesis hsa04918            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Glutathione metabolism hsa00480            Pathway Map 
  3D Structure
PDB ID: 1ALG 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -3.228014077 FZR = 0.441271053
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.636057109 FZR = 1
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALANYL GLUTAMINE . . . DGIdb
AMIFOSTINE . 2141  D06CIE  DGIdb
CARBOPLATIN . 426756  D0X7HM  DGIdb
CARMUSTINE . 2578  D01OXI  DGIdb
carmustine . 2578  D01OXI  DrugCentral
CARVEDILOL . 2585  D0W9LX  DGIdb
CEFOTAXIME . 5742673  D0D1HA  DGIdb
ENALAPRIL . 5388962  D00SEB  DGIdb
glutamic acid . . . DrugCentral
LANSOPRAZOLE . 9578005  D06YYD  DGIdb
LEVOFLOXACIN . 149096  D02RSN  DGIdb
lysine . . . DrugCentral
menadione . 4055  D03GET  DrugCentral
methylthioninium chloride . 6099  D09NYS  DrugCentral
nifedipine . 4485  D04OSE  DrugCentral
OFLOXACIN . 4583  D03NHW  DGIdb
ONDANSETRON . 4595  D0K7WK  DGIdb
OXIGLUTATIONE . . . DGIdb
QUERCETIN . 5280343  D0K8KX  DGIdb

Protein Sequence Information

MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
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