Host Protein General Information

  Protein Name
Tropomyosin alpha-3 chain
  Gene Name
TPM3
  Host Species
Homo sapiens
  Uniprot Entry Name
TPM3_HUMAN
  Protein Families
Tropomyosin family
  Subcellular Location
Cytoplasm; cytoskeleton
  External Link
NCBI Gene ID
7170
Uniprot ID
P06753
Ensembl ID
ENSG00000143549
HGNC ID
12012
  Related KEGG Pathway
Pathways in cancer hsa05200            Pathway Map 
Thyroid cancer hsa05216            Pathway Map 
Hypertrophic cardiomyopathy hsa05410            Pathway Map 
Dilated cardiomyopathy hsa05414            Pathway Map 
Motor proteins hsa04814            Pathway Map 
Cardiac muscle contraction hsa04260            Pathway Map 
Adrenergic signaling in cardiomyocytes hsa04261            Pathway Map 
  3D Structure
PDB ID: 6OTN 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -9.822719651 FZR = 8.2245E-20
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.000954553 FZR = 1
Dengue virus 3 (strain D3/SG/05K863DK1/2005) 3'UTR RNA Info RNA chromatography and quantitative mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
APAZIQUONE . 5813717  D0FP0R  DGIdb
CORTICOTROPIN . 16132265  D0R4HQ  DGIdb
EPINEPHRINE . 5816  D04PHC  DGIdb
METHOTREXATE . 126941  D0SV8E  DGIdb
MIDAZOLAM . 4192  D0U6LM  DGIdb
PROGESTERONE . 5994  D07BSQ  DGIdb
SIMVASTATIN . 54454  D0H0ND  DGIdb
THIOGUANINE . 2723601  D02ZXM  DGIdb

Protein Sequence Information

MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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