Host Protein General Information

  Protein Name
Aldo-keto reductase family 1 member A1
  Gene Name
AKR1A1
  Host Species
Homo sapiens
  Uniprot Entry Name
AK1A1_HUMAN
  Protein Families
Aldo/keto reductase family
  EC Number
1.1.1.19; 1.1.1.2; 1.1.1.20; 1.1.1.372; 1.1.1.54
  Subcellular Location
Cytoplasm; cytosol
  External Link
NCBI Gene ID
10327
Uniprot ID
P14550
Ensembl ID
ENSG00000117448
HGNC ID
380
  Related KEGG Pathway
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
Glycolysis / Gluconeogenesis hsa00010            Pathway Map 
Pentose and glucuronate interconversions hsa00040            Pathway Map 
Ascorbate and aldarate metabolism hsa00053            Pathway Map 
Pyruvate metabolism hsa00620            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Biosynthesis of cofactors hsa01240            Pathway Map 
Glycerolipid metabolism hsa00561            Pathway Map 
  3D Structure
PDB ID: 2ALR 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -3.602230168 FZR = 0.123991037
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 2.443828303 FZR = 1
Hepatitis E virus 3'UTR RNA Info RNA-protein interaction detection (RaPID) assay coupled to liquid chromatography with tandem mass spectrometry (LC-MS/MS) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney . . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
DOXORUBICIN . 31703  D07VLY  DGIdb
epalrestat . 1549120  D03KOZ  DrugCentral
tolrestat . 53359  D0Q7QY  DrugCentral
valproic acid . . . DrugCentral

Protein Sequence Information

MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY
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