Host Protein General Information

  Protein Name
Merlin
  Gene Name
NF2
  Host Species
Homo sapiens
  Uniprot Entry Name
MERL_HUMAN
  Subcellular Location
Nucleus; Cell projection
  External Link
NCBI Gene ID
4771
Uniprot ID
P35240
Ensembl ID
ENSG00000186575
HGNC ID
7773
  Related KEGG Pathway
Tight junction hsa04530            Pathway Map 
Hippo signaling pathway hsa04390            Pathway Map 
Hippo signaling pathway - multiple species hsa04392            Pathway Map 
  3D Structure
PDB ID: 1H4R 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 2.178686195 FZR = 1
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 13.27839444 FZR = 4.14E-37
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 0.0291621978210196 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h P = 0.0161485010015006 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h P = 0.00721623403737048 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
CARBOPLATIN . 426756  D0X7HM  DGIdb
CARBOPLATIN . 426756  D0X7HM  .
CISPLATIN . 5702198  D0U5HU  DGIdb
EVEROLIMUS . 6442177  D0K3QS  DGIdb
EVEROLIMUS . 6442177  D0K3QS  .
SELUMETINIB . 10127622  D0T5DP  .
SELUMETINIB . 10127622  D0T5DP  DGIdb
TEMSIROLIMUS . 6918289  D0ES1Q  .
TEMSIROLIMUS . 6918289  D0ES1Q  DGIdb

Protein Sequence Information

MAGAIASRMSFSSLKRKQPKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYTIKDTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAKSRVAFFEEL
    Click to Show/Hide