Host Protein General Information

  Protein Name
Protein kinase C iota type
  Gene Name
PRKCI
  Host Species
Homo sapiens
  Uniprot Entry Name
KPCI_HUMAN
  Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family, PKC subfamily
  EC Number
2.7.11.13
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
5584
Uniprot ID
P41743
Ensembl ID
ENSG00000163558
HGNC ID
9404
  Related KEGG Pathway
Platelet activation hsa04611            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Tight junction hsa04530            Pathway Map 
Insulin signaling pathway hsa04910            Pathway Map 
Rap1 signaling pathway hsa04015            Pathway Map 
Hippo signaling pathway hsa04390            Pathway Map 
Endocytosis hsa04144            Pathway Map 
  3D Structure
PDB ID: 1VD2 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .
Dengue virus 2 (strain NGC) 5'UTR - 3'UTR RNA Info UV cross-linking followed by antisense-mediated affinity purification and mass spectrometry HuH-7 Cells (Human hepatocellular carcinoma cell) . Liver 30 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
CEP-2563 . . D0KX1E  DGIdb
GSK-269962A . 16095342  D02ZQS  DGIdb
GSK-690693 . 16725726  D0MS3Z  DGIdb
ILORASERTIB . 46207586  D08HOM  DGIdb
MIDOSTAURIN . 9829523  D07NVU  DGIdb
QUERCETIN . 5280343  D0K8KX  DGIdb
ruboxistaurin . 153999  D0W3LI  DrugCentral
STAUROSPORINE . 44259  D0E3TC  DGIdb
UCN-01 . 72271  D0Z9VY  DGIdb

Protein Sequence Information

MPTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV
    Click to Show/Hide