Host Protein General Information

  Protein Name
Transcription factor ISGF-3 components p91/p84
  Gene Name
STAT1
  Host Species
Homo sapiens
  Uniprot Entry Name
STAT1_HUMAN
  Protein Families
Transcription factor STAT family
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
6772
Uniprot ID
P42224
Ensembl ID
ENSG00000115415
HGNC ID
11362
  Related KEGG Pathway
Chemokine signaling pathway hsa04062            Pathway Map 
Toll-like receptor signaling pathway hsa04620            Pathway Map 
NOD-like receptor signaling pathway hsa04621            Pathway Map 
C-type lectin receptor signaling pathway hsa04625            Pathway Map 
Th1 and Th2 cell differentiation hsa04658            Pathway Map 
Th17 cell differentiation hsa04659            Pathway Map 
Leishmaniasis hsa05140            Pathway Map 
Toxoplasmosis hsa05145            Pathway Map 
Tuberculosis hsa05152            Pathway Map 
Hepatitis C hsa05160            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Measles hsa05162            Pathway Map 
Influenza A hsa05164            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Kaposi sarcoma-associated herpesvirus infection hsa05167            Pathway Map 
Herpes simplex virus 1 infection hsa05168            Pathway Map 
Epstein-Barr virus infection hsa05169            Pathway Map 
Coronavirus disease - COVID-19 hsa05171            Pathway Map 
Inflammatory bowel disease hsa05321            Pathway Map 
Necroptosis hsa04217            Pathway Map 
Osteoclast differentiation hsa04380            Pathway Map 
JAK-STAT signaling pathway hsa04630            Pathway Map 
Prolactin signaling pathway hsa04917            Pathway Map 
Thyroid hormone signaling pathway hsa04919            Pathway Map 
AGE-RAGE signaling pathway in diabetic complications hsa04933            Pathway Map 
Growth hormone synthesis, secretion and action hsa04935            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Pancreatic cancer hsa05212            Pathway Map 
PD-L1 expression and PD-1 checkpoint pathway in cancer hsa05235            Pathway Map 
  3D Structure
PDB ID: 1BF5 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 2.381538847 FZR = 1
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.321756 FZR = 0.014194455
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h . .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
CISPLATIN . 5702198  D0U5HU  DGIdb
GARCINOL . 5281560  D03JNC  DGIdb
IPRIFLAVONE . 3747  D0R2OA  DGIdb
PICOPLATIN . 177358  D0T7GV  DGIdb
suramin . 5361  D0H2UB  DrugCentral

Protein Sequence Information

MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
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