Host Protein General Information

  Protein Name
Actin
  Gene Name
ACTC1
  Host Species
Homo sapiens
  Uniprot Entry Name
ACTC_HUMAN
  Protein Families
Actin family
  EC Number
3.6.4.-
  Subcellular Location
Cytoplasm; cytoskeleton
  External Link
NCBI Gene ID
70
Uniprot ID
P68032
Ensembl ID
ENSG00000159251
HGNC ID
143
  Related KEGG Pathway
Hypertrophic cardiomyopathy hsa05410            Pathway Map 
Dilated cardiomyopathy hsa05414            Pathway Map 
Motor proteins hsa04814            Pathway Map 
Cardiac muscle contraction hsa04260            Pathway Map 
Adrenergic signaling in cardiomyocytes hsa04261            Pathway Map 
  3D Structure
AlphaFold ID: P68032 
  2D PNG Download  
  mmCIF File Download   
  PDB File Download   

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -11.39650653 FZR = 4.36977E-27
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.432684724 FZR = 0.008692449
Zika virus (strain MR766) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 20 h MIST = 0.880140873 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
DEXAMETHASONE . 5743  D0IT2G  DGIdb

Protein Sequence Information

MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
    Click to Show/Hide