Host Protein General Information

  Protein Name
Transcription factor p65
  Gene Name
RELA
  Host Species
Homo sapiens
  Uniprot Entry Name
TF65_HUMAN
  Subcellular Location
Nucleus
  External Link
NCBI Gene ID
5970
Uniprot ID
Q04206
Ensembl ID
ENSG00000173039
HGNC ID
9955
  Related KEGG Pathway
Chemokine signaling pathway hsa04062            Pathway Map 
Neutrophil extracellular trap formation hsa04613            Pathway Map 
Toll-like receptor signaling pathway hsa04620            Pathway Map 
NOD-like receptor signaling pathway hsa04621            Pathway Map 
RIG-I-like receptor signaling pathway hsa04622            Pathway Map 
Cytosolic DNA-sensing pathway hsa04623            Pathway Map 
C-type lectin receptor signaling pathway hsa04625            Pathway Map 
IL-17 signaling pathway hsa04657            Pathway Map 
Th1 and Th2 cell differentiation hsa04658            Pathway Map 
Th17 cell differentiation hsa04659            Pathway Map 
T cell receptor signaling pathway hsa04660            Pathway Map 
B cell receptor signaling pathway hsa04662            Pathway Map 
Epithelial cell signaling in Helicobacter pylori infection hsa05120            Pathway Map 
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Shigellosis hsa05131            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Pertussis hsa05133            Pathway Map 
Legionellosis hsa05134            Pathway Map 
Yersinia infection hsa05135            Pathway Map 
Tuberculosis hsa05152            Pathway Map 
Leishmaniasis hsa05140            Pathway Map 
Chagas disease hsa05142            Pathway Map 
Toxoplasmosis hsa05145            Pathway Map 
Amoebiasis hsa05146            Pathway Map 
Hepatitis C hsa05160            Pathway Map 
Hepatitis B hsa05161            Pathway Map 
Measles hsa05162            Pathway Map 
Human cytomegalovirus infection hsa05163            Pathway Map 
Influenza A hsa05164            Pathway Map 
Human papillomavirus infection hsa05165            Pathway Map 
Human T-cell leukemia virus 1 infection hsa05166            Pathway Map 
Kaposi sarcoma-associated herpesvirus infection hsa05167            Pathway Map 
Herpes simplex virus 1 infection hsa05168            Pathway Map 
Epstein-Barr virus infection hsa05169            Pathway Map 
Human immunodeficiency virus 1 infection hsa05170            Pathway Map 
Coronavirus disease - COVID-19 hsa05171            Pathway Map 
Antifolate resistance hsa01523            Pathway Map 
Longevity regulating pathway hsa04211            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Transcriptional misregulation in cancer hsa05202            Pathway Map 
Viral carcinogenesis hsa05203            Pathway Map 
Chemical carcinogenesis - receptor activation hsa05207            Pathway Map 
Chemical carcinogenesis - reactive oxygen species hsa05208            Pathway Map 
PD-L1 expression and PD-1 checkpoint pathway in cancer hsa05235            Pathway Map 
Pancreatic cancer hsa05212            Pathway Map 
Prostate cancer hsa05215            Pathway Map 
Chronic myeloid leukemia hsa05220            Pathway Map 
Acute myeloid leukemia hsa05221            Pathway Map 
Small cell lung cancer hsa05222            Pathway Map 
Diabetic cardiomyopathy hsa05415            Pathway Map 
Lipid and atherosclerosis hsa05417            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Cellular senescence hsa04218            Pathway Map 
Osteoclast differentiation hsa04380            Pathway Map 
Insulin resistance hsa04931            Pathway Map 
Non-alcoholic fatty liver disease hsa04932            Pathway Map 
AGE-RAGE signaling pathway in diabetic complications hsa04933            Pathway Map 
Alcoholic liver disease hsa04936            Pathway Map 
Prolactin signaling pathway hsa04917            Pathway Map 
Adipocytokine signaling pathway hsa04920            Pathway Map 
Relaxin signaling pathway hsa04926            Pathway Map 
Inflammatory bowel disease hsa05321            Pathway Map 
Neurotrophin signaling pathway hsa04722            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
MAPK signaling pathway hsa04010            Pathway Map 
Ras signaling pathway hsa04014            Pathway Map 
cAMP signaling pathway hsa04024            Pathway Map 
NF-kappa B signaling pathway hsa04064            Pathway Map 
HIF-1 signaling pathway hsa04066            Pathway Map 
Sphingolipid signaling pathway hsa04071            Pathway Map 
PI3K-Akt signaling pathway hsa04151            Pathway Map 
TNF signaling pathway hsa04668            Pathway Map 
Cocaine addiction hsa05030            Pathway Map 
Mitophagy - animal hsa04137            Pathway Map 
  3D Structure
PDB ID: 1NFI 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Hepatitis E virus 3'UTR RNA Info RNA-protein interaction detection (RaPID) assay coupled to liquid chromatography with tandem mass spectrometry (LC-MS/MS) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney . . .
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 0.000128453945849677 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 9.30254812904301e-05 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 3 h P = 0.000249176554464078 .
Chikungunya virus (strain 181/25) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 0.2 h P = 0.000125809176284766 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ACACETIN . 5280442  D0NS1S  DGIdb
ANDROGRAPHOLIDE . 5318517  D04VIS  DGIdb
APIGENIN . 5280443  D00RIX  DGIdb
ARTESUNATE . 6917864  D0D4JO  DGIdb
CHRYSOERIOL . 5280666  D01FGM  DGIdb
CYNAROPICRIN . 119093  D0S2TZ  DGIdb
DEHYDROXYMETHYLEPOXYQUINOMICIN . 9881652  D0Y9GA  DGIdb
DEXAMETHASONE . 5743  D0IT2G  DGIdb
DIOSMETIN . 5281612  D00RFY  DGIdb
GEFITINIB . 123631  D09XZB  DGIdb
GOSSYPETIN . 5280647  D0Z7EL  DGIdb
INDOPROFEN . 3718  D0Q5PL  DGIdb
ISORHAMNETIN . 5281654  D07YDN  DGIdb
KAEMPFERIDE . 5281666  D04DYO  DGIdb
KAEMPFEROL . 5280863  D0G3TK  DGIdb
LUTEOLIN . 5280445  D04AIT  DGIdb
PARTHENOLIDE . 7251185  D0M4KE  DGIdb
PLUMBAGIN . 10205  D0P0IE  DGIdb
PYRROLIDINE DITHIOCARBAMATE . 65351  D0B0IJ  DGIdb
QUERCETIN . 5280343  D0K8KX  DGIdb
RESVERATROL . 445154  D0U3EP  DGIdb
RUTIN . 5280805  D09ALJ  DGIdb
SORBINIL . 337359  D02CGC  DGIdb
TAMARIXETIN . 5281699  D06PZE  DGIdb
VORICONAZOLE . 71616  D0N3VR  DGIdb

Protein Sequence Information

MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
    Click to Show/Hide