Host Protein General Information

  Protein Name
DNA dC->dU-editing enzyme APOBEC-3G
  Gene Name
APOBEC3G
  Host Species
Homo sapiens
  Uniprot Entry Name
ABC3G_HUMAN
  Protein Families
Cytidine and deoxycytidylate deaminase family
  EC Number
3.5.4.38
  Subcellular Location
Cytoplasm; Nucleus; Cytoplasm
  External Link
NCBI Gene ID
60489
Uniprot ID
Q9HC16
Ensembl ID
ENSG00000239713
HGNC ID
17357
  Related KEGG Pathway
Human immunodeficiency virus 1 infection hsa05170            Pathway Map 
Viral life cycle - HIV-1 hsa03250            Pathway Map 
  3D Structure
PDB ID: 2JYW 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Human immunodeficiency virus type 1 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) and immunoprecipitation (IP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 48 h . .
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -4.56691608 FZR = 0.002435164
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -1.492383414 FZR = 1

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
3-O-METHYLQUERCETIN . 5280681  D0L9EF  DGIdb
APOMORPHINE HYDROCHLORIDE HEMIHYDRATE . 107882  D01KYP  DGIdb
BENZOQUINONE . 4650  D0M2EM  DGIdb
CEFOTETAN . 53025  D0AP9T  DGIdb
CGS-15943 . 2690  D0Q6WX  DGIdb
CHEMBL1287981 . 5940197  D06CHV  DGIdb
CHEMBL313737 . 58144  D0BQ8M  DGIdb
CHEMBL428064 . 659101  D0Q2KK  DGIdb
CHEMBL429095 . 262093  D0J1KH  DGIdb
CHEMBL605003 . 5312137  D0CE3R  DGIdb
CHEMBL72365 . 5924208  D0Z5TQ  DGIdb
CHEMBL88147 . 393595  D0Y8EU  DGIdb
ELLIPTECINE . 3213  D00DNY  DGIdb
MYRICETIN . 5281672  D0T3PW  DGIdb
SB-216763 . 176158  D0A1YQ  DGIdb

Protein Sequence Information

MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
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