Host Protein General Information

  Protein Name
Glutathione S-transferase P
  Gene Name
GSTP1
  Host Species
Homo sapiens
  Uniprot Entry Name
GSTP1_HUMAN
  Protein Families
GST superfamily, Pi family
  EC Number
2.5.1.18
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
2950
Uniprot ID
P09211
Ensembl ID
ENSG00000077235
HGNC ID
4638
  Related KEGG Pathway
Glutathione metabolism hsa00480            Pathway Map 
Metabolism of xenobiotics by cytochrome P450 hsa00980            Pathway Map 
Drug metabolism - cytochrome P450 hsa00982            Pathway Map 
Drug metabolism - other enzymes hsa00983            Pathway Map 
Metabolic pathways hsa01100            Pathway Map 
Platinum drug resistance hsa01524            Pathway Map 
Pathways in cancer hsa05200            Pathway Map 
Chemical carcinogenesis - DNA adducts hsa05204            Pathway Map 
Prostate cancer hsa05215            Pathway Map 
Hepatocellular carcinoma hsa05225            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
  3D Structure
PDB ID: 10GS 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .
Zika virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 5.120791657 FZR = 0.000166124
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = 2.383166139 FZR = 1
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) Not Specified Virus Region RNA Info ChIRP-MS Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) . Liver 48 h FDR <= 0.05 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/IPBCAMS-YL01/2020) 3'UTR RNA Info ChIRP-MS Huh7.5.1 cells . Liver 30 h MIST = 0.685538835 .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h Saint score = 1 MIST = 1.015
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h Saint score = 0.69 MIST = 1.244

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ALCOHOL . 702  D00AMQ  DGIdb
AZACITIDINE . 9444  D09FAZ  DGIdb
BLEOMYCIN . 5360373  D06UVD  DGIdb
BUSULFAN . 2478  D07SUG  DGIdb
CAMPTOTHECIN . 24360  D09YDM  DGIdb
CANFOSFAMIDE . 5312109  D0A9SA  DGIdb
CARBOPLATIN . 426756  D0X7HM  DGIdb
CISPLATIN . 5702198  D0U5HU  DGIdb
clomipramine . 2801  D0ZS8P  DrugCentral
CURCUMIN . 969516  D07SDQ  DGIdb
CYCLOPHOSPHAMIDE . 2907  D0CT9C  DGIdb
CYTARABINE . 6253  D07XSN  DGIdb
DAUNORUBICIN . 30323  D01XWG  DGIdb
DECITABINE . 451668  D0X5XU  DGIdb
DEXAMETHASONE . 5743  D0IT2G  DGIdb
DITIOCARB . . . DGIdb
DOCETAXEL . 148124  D0O5WP  DGIdb
DOXORUBICIN . 31703  D07VLY  DGIdb
DROLOXIFENE . 3033767  D0R2JS  DGIdb
EPIRUBICIN . 41867  D0C9XJ  DGIdb
ethacrynic acid . 3278  D06TNL  DrugCentral
ETOPOSIDE . 36462  D0B7EB  DGIdb
EXATECAN MESYLATE . 151115  D01FUC  DGIdb
EZATIOSTAT . 5310939  D0F5VD  DGIdb
FLUOROURACIL . 3385  D05LEO  DGIdb
HYDROQUINONE . 785  D03UOT  DGIdb
IFOSFAMIDE . 3690  D02TLO  DGIdb
IRINOTECAN HYDROCHLORIDE . 60838  D07HOB  DGIdb
ISONIAZID . 3767  D09XQF  DGIdb
LEUCOVORIN . . . DGIdb
LYCOPENE . . . DGIdb
MELPHALAN . 460612  D00FGO  DGIdb
OMEPRAZOLE . 4594  D01XNB  DGIdb
OXALIPLATIN . 9887053  D0Y3ME  DGIdb
PACLITAXEL . . . DGIdb
PERFOSFAMIDE . 9554809  D03ZIS  DGIdb
PREDNISONE . 5865  D0IL7L  DGIdb
PYRIMETHAMINE . 4993  D0C0SK  DGIdb
RESVERATROL . 445154  D0U3EP  DGIdb
RIFAMPIN . 135398735  D0G3DL  DGIdb
SELENOMETHIONINE . . . DGIdb
SULFORAPHANE . 5350  D0X4IO  DGIdb
THIOTEPA . 5453  D00YZA  DGIdb
VERAPAMIL . 2520  D0R0FE  DGIdb
VITAMIN E . 14985  D02TQO  DGIdb
Vitamin E . 14985  D02TQO  DrugCentral

Protein Sequence Information

MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
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