Host Protein General Information

  Protein Name
Thioredoxin
  Gene Name
TXN
  Host Species
Homo sapiens
  Uniprot Entry Name
THIO_HUMAN
  Protein Families
Thioredoxin family
  Subcellular Location
Nucleus
  External Link
NCBI Gene ID
7295
Uniprot ID
P10599
Ensembl ID
ENSG00000136810
HGNC ID
12435
  Related KEGG Pathway
NOD-like receptor signaling pathway hsa04621            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Fluid shear stress and atherosclerosis hsa05418            Pathway Map 
Parkinson disease hsa05012            Pathway Map 
  3D Structure
PDB ID: 1AIU 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -10.92707854 FZR = 8.41042E-25
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -2.563357871 FZR = 1
Influenza A virus (strain California/7/2004 (H3N2)) 5'UTR - 3'UTR RNA Info VIRal Cross-Linking And Solid-phase Purification (VIR-CLASP) BHK-21 Cells (Small hamster kidney fibroblast) . Kidney 1 h P = 0.00226327317654591 .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Thiouracil cross-linking mass spectrometry (TUX-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver 28 h MIST = 1.92 .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Thiouracil cross-linking mass spectrometry (TUX-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver 28 h . .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
PX-12 . 219104  D04JTD  DGIdb

Protein Sequence Information

MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
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