Host Protein General Information

  Protein Name
Tubulin alpha-1B chain
  Gene Name
TUBA1B
  Host Species
Homo sapiens
  Uniprot Entry Name
TBA1B_HUMAN
  Protein Families
Tubulin family
  EC Number
3.6.5.-
  Subcellular Location
Cytoplasm; cytoskeleton
  External Link
NCBI Gene ID
10376
Uniprot ID
P68363
Ensembl ID
ENSG00000123416
HGNC ID
18809
  Related KEGG Pathway
Pathogenic Escherichia coli infection hsa05130            Pathway Map 
Salmonella infection hsa05132            Pathway Map 
Apoptosis hsa04210            Pathway Map 
Motor proteins hsa04814            Pathway Map 
Tight junction hsa04530            Pathway Map 
Gap junction hsa04540            Pathway Map 
Alzheimer disease hsa05010            Pathway Map 
Parkinson disease hsa05012            Pathway Map 
Amyotrophic lateral sclerosis hsa05014            Pathway Map 
Huntington disease hsa05016            Pathway Map 
Prion disease hsa05020            Pathway Map 
Pathways of neurodegeneration - multiple diseases hsa05022            Pathway Map 
Phagosome hsa04145            Pathway Map 
  3D Structure
PDB ID: 2E4H 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Dengue virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .
Zika virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h . .
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -10.84050927 FZR = 2.17033E-24
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -5.807683132 FZR = 7.00E-06
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) N region RNA Info RNA pull-down assays; liquid chromatography with tandem mass spectrometry (LC-MS/MS); Wilcoxon test; MS2 affinity purification coupled with liquid chromatography-mass spectrometry (MAMS) Calu-3 cell line . Liver . P value < 0.05 .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/IPBCAMS-YL01/2020) 3'UTR RNA Info ChIRP-MS Huh7.5.1 cells . Liver 30 h MIST = 0.685526969 .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Thiouracil cross-linking mass spectrometry (TUX-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver 28 h MIST = 1.98 .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Thiouracil cross-linking mass spectrometry (TUX-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver 28 h . .
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h Saint score = 1 MIST = 6.614
Dengue virus 2 (strain 16681) 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) . Liver 48 h Saint score = 0 MIST = 0.000

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
ABT-751 . 3035714  D09EHO  DGIdb
BRENTUXIMAB VEDOTIN . ?  D03TIS  DGIdb
CABAZITAXEL . 9854073  D02HSB  DGIdb
COLCHICINE . 6167  D09DHY  DGIdb
CROLIBULIN . 23649181  D04RSR  DGIdb
CURCUMIN . 969516  D07SDQ  DGIdb
DAVUNETIDE . . D0V1FF  DGIdb
DOCETAXEL . 148124  D0O5WP  DGIdb
ERIBULIN MESYLATE . 17755248  D0XQ5X  DGIdb
FOSBRETABULIN DISODIUM . 100154  D09OKZ  DGIdb
INDIBULIN . 2929  D04NXL  DGIdb
IXABEPILONE . 6445540  D0W2EK  DGIdb
LARGAZOLE . 24757913  D0Z8PX  DGIdb
LEXIBULIN . . D01JNE  DGIdb
PACLITAXEL . . . DGIdb
PLINABULIN . 9949641  D0ZE1O  DGIdb
PODOFILOX . 10607  D0D4HN  DGIdb
SAGOPILONE . 11284169  D0F6YW  DGIdb
VERUBULIN . 11414799  D09BOH  DGIdb
VINBLASTINE . 13342  D0W9MM  DGIdb
VINCRISTINE . 5978  D09QVV  DGIdb
VINFLUNINE . 6918295  D0OT9S  DGIdb
VINORELBINE . 5311497  D01HTL  DGIdb
VINORELBINE TARTRATE . 5311497  D01HTL  DGIdb
VORINOSTAT . 5311  D0E7PQ  DGIdb

Protein Sequence Information

MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
    Click to Show/Hide