Host Protein General Information

  Protein Name
DNA dC->dU-editing enzyme APOBEC-3F
  Gene Name
APOBEC3F
  Host Species
Homo sapiens
  Uniprot Entry Name
ABC3F_HUMAN
  Protein Families
Cytidine and deoxycytidylate deaminase family
  EC Number
3.5.4.38
  Subcellular Location
Cytoplasm
  External Link
NCBI Gene ID
200316
Uniprot ID
Q8IUX4
Ensembl ID
ENSG00000128394
HGNC ID
17356
  Related KEGG Pathway
Human immunodeficiency virus 1 infection hsa05170            Pathway Map 
Viral life cycle - HIV-1 hsa03250            Pathway Map 
  3D Structure
PDB ID: 3WUS 
FASTA   Download
  2D PNG Download  
PDB File Download

Full List of Virus RNA Interacting with This Protien

Virus Name Binding Region RNA Info Detection Method Infection Cell Cell ID Cell Originated Tissue Infection Time Interaction Score 1 Interaction Score 2
Human immunodeficiency virus type 1 5'UTR - 3'UTR RNA Info UV cross-linking (UVX) and immunoprecipitation (IP) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 48 h . .
Sindbis virus 5'UTR - 3'UTR RNA Info comparative RIC HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 18 h MIST = 0.981331198 .
Encephalomyocarditis virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -9.043160658 FZR = 1.33028E-16
Influenza A virus 5'UTR - 3'UTR RNA Info Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) HuH-7.5 Cells (Human hepatocellular carcinoma cell) . Liver . Z-score = -0.559270536 FZR = 1
Human immunodeficiency virus type 1 (strain NL4-3) GAG RNA Info Crosslinking with immunoprecipitation followed by sequencing (CLIP-seq) HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) . Kidney 48 h . .
Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/England/02/2020) Not Specified Virus Region RNA Info UV protein-RNA crosslinking; RNA interactome capture (cRIC); RNA antisense purification coupled with mass spectrometry (RAP-MS) Calu-3 cells (Human lung cancer cells) . Lung 24 h adj.P.Val = 0.055 .

Potential Drug(s) that Targets This Protein

Drug Name DrunkBank ID Pubchem ID TTD ID REF
3-O-METHYLQUERCETIN . 5280681  D0L9EF  DGIdb
8-AZAGUANINE . 135403646  D01OHV  DGIdb
CHEMBL1287981 . 5940197  D06CHV  DGIdb
CHEMBL605003 . 5312137  D0CE3R  DGIdb
ELLIPTECINE . 3213  D00DNY  DGIdb
SB-216763 . 176158  D0A1YQ  DGIdb

Protein Sequence Information

MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
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