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| Strain Information | Strain Name |
Hepatitis C virus
|
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|---|---|---|---|---|---|---|---|---|---|
| Strain Family |
Flaviviridae
|
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| RNA Binding Site |
5'UTR - 3'UTR
|
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| Virus Information | Virus Name |
Hepatitis C virus (HCV)
|
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| Taxonomy ID | 11103 | ||||||||
| GeneBank ID | AJ132997 | ||||||||
Full list of proteins interacting with the 5'UTR - 3'UTR of this Strain
| Protein Name | Uniprot ID | Host Species | Pro Info | Detection Method | Infection Cell | Cell ID | Cell Originated Tissue | Infection Time | Interaction Score | Fold Change |
|---|---|---|---|---|---|---|---|---|---|---|
| Antiviral innate immune response receptor RIG-I | O95786 | Homo sapiens | Pro Info | . | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| ATP-dependent RNA helicase A | Q08211 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Caprin-1 | Q14444 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| eIF3b | P55884 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| eIF3c | Q99613 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| eIF3e | O77410 | Drosophila melanogaster | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| eIF3f | O00303 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Gem-associated protein 5 | Q8TEQ6 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Heat shock cognate 71 kDa protein | P11142 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Heterogeneous nuclear ribonucleoprotein A/B | Q99729 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Heterogeneous nuclear ribonucleoprotein A1 | P09651 | Homo sapiens | Pro Info | Co-immunoprecipitation assays (Co-IP) | B95a Cells (Marmoset lymphoblastoid cell line) | . | . | . | . | . |
| Polyadenylate-binding protein 1 | P11940 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Polyadenylate-binding protein 2 | Q86U42 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | O15296 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| Protein Fe65-like 2 | O95704 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
| RNA-binding protein 24 | Q9BX46 | Homo sapiens | Pro Info | Flag-Assay | HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) | . | Liver | 72 h | . | . |
| RNA-binding protein 25 | P49756 | Homo sapiens | Pro Info | Flag-Assay | HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) | . | Kidney | . | . | . |
| RNA-binding protein 26 | Q5T8P6 | Homo sapiens | Pro Info | Western blot (WB), co-immunoprecipitation (Co-IP) and immunofluorescence analyses (IFA) | HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) | . | Kidney | . | . | . |
| RP-A p70 | P27694 | Homo sapiens | Pro Info | Mass spectrometry (MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 1 h | . | . |
Functional Go Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| GO Term | GO Category | GO ID | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|---|
| RNA Binding | Molecular Function |
GO:0003723
|
4.43E-11 | 37.24781675 | 1048.770568 |
| mRNA Binding | Molecular Function |
GO:0003729
|
1.68E-07 | 41.80060606 | 803.5293208 |
| Translation Initiation Factor Activity | Molecular Function |
GO:0003743
|
1.44E-06 | 143.7405405 | 2396.132209 |
| Single-Stranded RNA Binding | Molecular Function |
GO:0003727
|
0.00016419 | 93.4734375 | 1088.561952 |
| G-rich Strand Telomeric DNA Binding | Molecular Function |
GO:0098505
|
0.000459871 | 335.697479 | 3488.774622 |
| Sequence-Specific mRNA Binding | Molecular Function |
GO:1990825
|
0.000501277 | 261.0718954 | 2602.868539 |
| Single-Stranded Telomeric DNA Binding | Molecular Function |
GO:0043047
|
0.000501277 | 261.0718954 | 2602.868539 |
| Ribosome Binding | Molecular Function |
GO:0043022
|
0.000640694 | 45.5007622 | 436.39807 |
| mRNA 3'-UTR Binding | Molecular Function |
GO:0003730
|
0.000736581 | 41.43958333 | 386.3356989 |
| Single-Stranded DNA Binding | Molecular Function |
GO:0003697
|
0.000736581 | 40.09677419 | 370.0288311 |
| RNA Polymerase Binding | Molecular Function |
GO:0070063
|
0.000786115 | 156.5960784 | 1420.013279 |
| poly Binding | Molecular Function |
GO:0008143
|
0.001582393 | 102.0869565 | 845.4227697 |
| pre-mRNA Binding | Molecular Function |
GO:0036002
|
0.002095197 | 83.83613445 | 663.3671793 |
| Poly-Purine Tract Binding | Molecular Function |
GO:0070717
|
0.002095197 | 80.94117647 | 635.1080722 |
| Regulatory RNA Binding | Molecular Function |
GO:0061980
|
0.003598393 | 58.65 | 424.4327993 |
| Purine Ribonucleoside Triphosphate Binding | Molecular Function |
GO:0035639
|
0.004332633 | 11.0220339 | 77.005211 |
| Double-Stranded RNA Binding | Molecular Function |
GO:0003725
|
0.007571131 | 37.19514472 | 236.8470596 |
| ATP Binding | Molecular Function |
GO:0005524
|
0.009188953 | 13.38654891 | 81.88377469 |
| Adenyl Ribonucleotide Binding | Molecular Function |
GO:0032559
|
0.011627519 | 12.0557598 | 70.25409369 |
| 3'-5' RNA Helicase Activity | Molecular Function |
GO:0034458
|
0.016163835 | 277.4583333 | 1484.79735 |
| Cytoplasmic Stress Granule | Cellular Component |
GO:0010494
|
0.001907299 | 51.13356164 | 507.5327432 |
| Nucleus | Cellular Component |
GO:0005634
|
0.017068592 | 4.763041778 | 33.53624242 |
| Cytoskeleton | Cellular Component |
GO:0005856
|
0.025864757 | 8.688403361 | 53.3375423 |
| Intracellular Membrane-Bounded Organelle | Cellular Component |
GO:0043231
|
0.025864757 | 3.945270139 | 22.8343772 |
| Actin Cytoskeleton | Cellular Component |
GO:0015629
|
0.025864757 | 11.3755787 | 64.47489472 |
| Focal Adhesion | Cellular Component |
GO:0005925
|
0.025864757 | 9.568847656 | 49.72931787 |
| Cell-Substrate Junction | Cellular Component |
GO:0030055
|
0.025864757 | 9.36973852 | 48.16288218 |
| RISC-loading Complex | Cellular Component |
GO:0070578
|
0.025864757 | 184.9537037 | 927.700129 |
| Clathrin-Sculpted Gamma-Aminobutyric Acid Transport Vesicle | Cellular Component |
GO:0061200
|
0.025864757 | 184.9537037 | 927.700129 |
| Clathrin-Sculpted Gamma-Aminobutyric Acid Transport Vesicle Membrane | Cellular Component |
GO:0061202
|
0.025864757 | 184.9537037 | 927.700129 |
| Nuclear Inclusion Body | Cellular Component |
GO:0042405
|
0.033545355 | 123.2839506 | 574.5677164 |
| RISC Complex | Cellular Component |
GO:0016442
|
0.039921044 | 92.44907407 | 406.7303182 |
| Endoribonuclease Complex | Cellular Component |
GO:1902555
|
0.048102217 | 69.32291667 | 286.5143387 |
| Intracellular Non-Membrane-Bounded Organelle | Cellular Component |
GO:0043232
|
0.066596687 | 4.207108872 | 15.70768173 |
| Polysomal Ribosome | Cellular Component |
GO:0042788
|
0.068325369 | 41.05761317 | 149.4080626 |
| Ribosome | Cellular Component |
GO:0005840
|
0.137501516 | 18.44537037 | 53.03215997 |
| Bicellular Tight Junction | Cellular Component |
GO:0005923
|
0.150299747 | 13.82013889 | 35.93852915 |
| P-body | Cellular Component |
GO:0000932
|
0.150299747 | 13.48170732 | 34.74163891 |
| Autophagosome | Cellular Component |
GO:0005776
|
0.150299747 | 13.48170732 | 34.74163891 |
| Lysosomal Lumen | Cellular Component |
GO:0043202
|
0.150299747 | 13.00392157 | 33.06607217 |
| Formation Of Cytoplasmic Translation Initiation Complex | Biological Process |
GO:0001732
|
1.73E-07 | 532.56 | 11327.81858 |
| protein-RNA Complex Assembly | Biological Process |
GO:0022618
|
6.02E-07 | 63.58012821 | 1228.989793 |
| Cytoplasmic Translational Initiation | Biological Process |
GO:0002183
|
1.56E-06 | 204.6666667 | 3677.925935 |
| Regulation Of Translation | Biological Process |
GO:0006417
|
1.79E-06 | 46.58948195 | 817.4960793 |
| Negative Regulation Of mRNA Catabolic Process | Biological Process |
GO:1902373
|
3.44E-06 | 143.7405405 | 2396.132209 |
| mRNA Splicing, Via Spliceosome | Biological Process |
GO:0000398
|
6.20E-05 | 34.28398058 | 465.0571218 |
| Regulation Of Cytoplasmic Translation | Biological Process |
GO:2000765
|
6.20E-05 | 178.2142857 | 2395.58312 |
| Positive Regulation Of Translation | Biological Process |
GO:0045727
|
0.000109423 | 50.96666667 | 649.3813079 |
| Negative Regulation Of Nuclear-Transcribed mRNA Catabolic Process, Nonsense-Mediated Decay | Biological Process |
GO:2000623
|
0.000283563 | 783.4509804 | 9143.887447 |
| mRNA Stabilization | Biological Process |
GO:0048255
|
0.000449125 | 74.74125 | 822.9578648 |
| Regulation Of Alternative mRNA Splicing, Via Spliceosome | Biological Process |
GO:0000381
|
0.000449125 | 74.74125 | 822.9578648 |
| RNA Splicing, Via Transesterification Reactions With Bulged Adenosine As Nucleophile | Biological Process |
GO:0000377
|
0.000551351 | 30.00757576 | 321.6414698 |
| CRD-mediated mRNA Stabilization | Biological Process |
GO:0070934
|
0.000817999 | 293.7205882 | 2987.148937 |
| Regulation Of Nuclear-Transcribed mRNA Catabolic Process, Nonsense-Mediated Decay | Biological Process |
GO:2000622
|
0.000817999 | 293.7205882 | 2987.148937 |
| mRNA Processing | Biological Process |
GO:0006397
|
0.000868005 | 25.10603175 | 252.1073912 |
| Negative Regulation Of Nuclear-Transcribed mRNA Catabolic Process, Deadenylation-Dependent Decay | Biological Process |
GO:1900152
|
0.00087431 | 261.0718954 | 2602.868539 |
| Cellular Response To Exogenous dsRNA | Biological Process |
GO:0071360
|
0.001216114 | 195.7745098 | 1853.612484 |
| Positive Regulation Of Response To Cytokine Stimulus | Biological Process |
GO:0060760
|
0.001216114 | 195.7745098 | 1853.612484 |
| Positive Regulation Of Cytoplasmic Translation | Biological Process |
GO:2000767
|
0.001216114 | 195.7745098 | 1853.612484 |
| Regulation Of mRNA Splicing, Via Spliceosome | Biological Process |
GO:0048024
|
0.001379106 | 40.98214286 | 380.7663633 |
Functional KEGG Enrichment analysis of those proteins interacting with the 5'UTR - 3'UTR of this Strain
| Pathways | Category | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|
| RNA transport | KEGG Pathway | 3.66E-07 | 50.77179487 | 915.8961336 |
| Spliceosome | KEGG Pathway | 0.00458579 | 25.29846939 | 200.1240881 |
| mRNA surveillance pathway | KEGG Pathway | 0.032075325 | 24.36887255 | 135.4892689 |
| Mismatch repair | KEGG Pathway | 0.135217488 | 50.40151515 | 193.2118011 |
| DNA replication | KEGG Pathway | 0.141027196 | 31.66031746 | 107.3683212 |
| Homologous recombination | KEGG Pathway | 0.141027196 | 27.69583333 | 90.38385304 |
| Nucleotide excision repair | KEGG Pathway | 0.141027196 | 24.07608696 | 75.34749261 |
| Fanconi anemia pathway | KEGG Pathway | 0.141027196 | 20.88888889 | 62.53826708 |
| Legionellosis | KEGG Pathway | 0.141027196 | 19.76686508 | 58.13687387 |
| Arachidonic acid metabolism | KEGG Pathway | 0.141027196 | 18.44537037 | 53.03215997 |
| Antigen processing and presentation | KEGG Pathway | 0.150983224 | 14.36075036 | 37.86712629 |
| RNA degradation | KEGG Pathway | 0.150983224 | 14.17592593 | 37.20550752 |
| Longevity regulating pathway | KEGG Pathway | 0.170175775 | 10.93509351 | 26.01759123 |
| Toxoplasmosis | KEGG Pathway | 0.170175775 | 9.944944945 | 22.77585081 |
| Serotonergic synapse | KEGG Pathway | 0.170175775 | 9.855654762 | 22.48813067 |
| Estrogen signaling pathway | KEGG Pathway | 0.182586475 | 8.106617647 | 17.02228515 |
| Measles | KEGG Pathway | 0.182586475 | 7.988325282 | 16.6651952 |
| Hepatitis C | KEGG Pathway | 0.18926389 | 7.060185185 | 13.92539446 |
| Protein processing in endoplasmic reticulum | KEGG Pathway | 0.18926389 | 6.474183007 | 12.25657631 |
| Influenza A | KEGG Pathway | 0.18926389 | 6.435997401 | 12.14959621 |
Full list of Host ncRNAs interacting with the Virus RNA
| HncRNA | Host Species | HncRNA Detail | PMID | Source | Target Gene | Target Gene ID | Target Gene Source | PMID | Source |
|---|---|---|---|---|---|---|---|---|---|
| hsa-miR-122-3p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | MCAT | . | miRTarBase | 27855320 | miRTarBase |
| hsa-miR-122-5p | Homo sapiens | HncRNA Info | 21821155 | ViRBase | ZNF395 | . | miRSponge | 23221562 | miRSponge |
| hsa-miR-122-5p | Homo sapiens | HncRNA Info | 16141076 | ViRBase | ZNF395 | . | miRSponge | 23221562 | miRSponge |
| hsa-miR-122-5p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | ZNF395 | . | miRSponge | 23221562 | miRSponge |
| hsa-miR-122-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | ZNF395 | . | miRSponge | 23221562 | miRSponge |
| hsa-miR-1252-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | LCE1B | . | StarBase | . | StarBase |
| hsa-miR-196a-1-3p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | . | . | . | . | . |
| hsa-miR-196a-3p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | FGF2 | . | miRTarBase | 28317323 | miRTarBase |
| hsa-miR-196a-5p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | ZNRD2 | . | miRTarBase | 27678369 | miRTarBase |
| hsa-miR-196b-3p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | PSMB1 | . | StarBase | . | StarBase |
| hsa-miR-196b-5p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | TGFBR2 | . | miRTarBase | 26940097 | miRTarBase |
| hsa-miR-199a-5p | Homo sapiens | HncRNA Info | 24871972 | ViRBase | WNT2 | . | miRTarBase | 23764775 | miRTarBase |
| hsa-miR-199a-5p | Homo sapiens | HncRNA Info | 21821155 | ViRBase | WNT2 | . | miRTarBase | 23764775 | miRTarBase |
| hsa-miR-505-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | PDK2 | . | StarBase | . | StarBase |
| hsa-miR-509-3p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | YAP1 | . | miRTarBase | 27036018 | miRTarBase |
| hsa-miR-509-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | YWHAG | . | miRTarBase | 27894843 | miRTarBase |
| hsa-miR-548c-3p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | TWIST1 | . | miRTarBase | 26762267 | miRTarBase |
| hsa-miR-548c-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | ENPP4 | . | StarBase | . | StarBase |
| hsa-miR-651-3p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | DGAT2L6 | . | StarBase | . | StarBase |
| hsa-miR-939-5p | Homo sapiens | HncRNA Info | 32751663 | ViRBase | SLC34A2 | . | miRTarBase | 28114937 | miRTarBase |
| miR-Core | Homo sapiens | HncRNA Info | WO_2011_109380_A1 | ViRBase | . | . | . | . | . |
| miR-NS5B | Homo sapiens | HncRNA Info | WO_2011_109380_A1 | ViRBase | . | . | . | . | . |
| miR-UTR1 | Homo sapiens | HncRNA Info | WO_2011_109380_A1 | ViRBase | . | . | . | . | . |
| miR-UTR2 | Homo sapiens | HncRNA Info | WO_2011_109380_A1 | ViRBase | . | . | . | . | . |
| miR-UTR3 | Homo sapiens | HncRNA Info | WO_2011_109380_A1 | ViRBase | . | . | . | . | . |
Host ncRNA GO Enrichment
| GO Term | GO Category | GO ID | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|---|
| Acyltransferase Activity, Transferring Groups Other Than Amino-Acyl Groups | GO Molecular Function |
GO:0016747
|
0.040646872 | 45.90322581 | 309.6797874 |
| Diacylglycerol O-acyltransferase Activity | GO Molecular Function |
GO:0004144
|
0.040646872 | 333 | 1839.150909 |
| Sodium Ion Binding | GO Molecular Function |
GO:0031402
|
0.040646872 | 266.3866667 | 1422.778691 |
| Transcription Cis-Regulatory Region Binding | GO Molecular Function |
GO:0000976
|
0.040646872 | 9.560509554 | 49.09471475 |
| Activin Receptor Activity | GO Molecular Function |
GO:0017002
|
0.040646872 | 190.2571429 | 961.5775797 |
| Phosphate Ion Binding | GO Molecular Function |
GO:0042301
|
0.040646872 | 166.4666667 | 821.7936241 |
| Type I Transforming Growth Factor Beta Receptor Binding | GO Molecular Function |
GO:0034713
|
0.040646872 | 166.4666667 | 821.7936241 |
| Transforming Growth Factor Beta Receptor Activity | GO Molecular Function |
GO:0005024
|
0.040646872 | 147.962963 | 714.9125872 |
| Fatty Acid Synthase Activity | GO Molecular Function |
GO:0004312
|
0.040646872 | 147.962963 | 714.9125872 |
| Cytokine Activity | GO Molecular Function |
GO:0005125
|
0.040646872 | 16.07792208 | 76.26589742 |
| Sodium:Phosphate Symporter Activity | GO Molecular Function |
GO:0005436
|
0.040646872 | 133.16 | 630.7474631 |
| Insulin-Like Growth Factor Receptor Binding | GO Molecular Function |
GO:0005159
|
0.043485053 | 110.9555556 | 507.117753 |
| Alkali Metal Ion Binding | GO Molecular Function |
GO:0031420
|
0.043485053 | 102.4153846 | 460.5338013 |
| Transmembrane Receptor Protein Serine/Threonine Kinase Activity | GO Molecular Function |
GO:0004675
|
0.043485053 | 95.0952381 | 421.091823 |
| Chemokine Binding | GO Molecular Function |
GO:0019956
|
0.04560806 | 83.2 | 358.0671609 |
| Transforming Growth Factor Beta Receptor Binding | GO Molecular Function |
GO:0005160
|
0.04560806 | 78.30196078 | 332.5412032 |
| Transforming Growth Factor Beta Binding | GO Molecular Function |
GO:0050431
|
0.046871407 | 66.54666667 | 272.4340598 |
| bHLH Transcription Factor Binding | GO Molecular Function |
GO:0043425
|
0.046871407 | 63.37460317 | 256.5235419 |
| Fibroblast Growth Factor Receptor Binding | GO Molecular Function |
GO:0005104
|
0.046871407 | 63.37460317 | 256.5235419 |
| DNA-binding Transcription Factor Binding | GO Molecular Function |
GO:0140297
|
0.051357776 | 10.05306122 | 38.90019441 |
| Ficolin-1-Rich Granule | GO Cellular Component |
GO:0101002
|
0.152368366 | 15.54317111 | 72.73921292 |
| Intracellular Organelle Lumen | GO Cellular Component |
GO:0070013
|
0.152368366 | 5.175669582 | 18.35317576 |
| Brush Border Membrane | GO Cellular Component |
GO:0031526
|
0.152368366 | 34.09401709 | 117.8503469 |
| Mitochondrial Matrix | GO Cellular Component |
GO:0005759
|
0.152368366 | 7.94455686 | 27.34646701 |
| Serine/Threonine Protein Kinase Complex | GO Cellular Component |
GO:1902554
|
0.152368366 | 22.51412429 | 68.86238459 |
| Ficolin-1-Rich Granule Membrane | GO Cellular Component |
GO:0101003
|
0.152368366 | 22.51412429 | 68.86238459 |
| Caveola | GO Cellular Component |
GO:0005901
|
0.152368366 | 21.77377049 | 65.90020062 |
| Plasma Membrane Raft | GO Cellular Component |
GO:0044853
|
0.175020347 | 16.38106996 | 45.12090295 |
| Cell Projection Membrane | GO Cellular Component |
GO:0031253
|
0.188044675 | 12.74358974 | 32.05988938 |
| Cytoplasmic Vesicle Lumen | GO Cellular Component |
GO:0060205
|
0.188044675 | 11.61988304 | 28.21896974 |
| Ficolin-1-Rich Granule Lumen | GO Cellular Component |
GO:1904813
|
0.188044675 | 10.85355191 | 25.66021587 |
| Tertiary Granule | GO Cellular Component |
GO:0070820
|
0.214931187 | 8.208281573 | 17.26404645 |
| Membrane Raft | GO Cellular Component |
GO:0045121
|
0.214931187 | 7.863492063 | 16.22655539 |
| Vesicle | GO Cellular Component |
GO:0031982
|
0.27086069 | 5.626780627 | 9.892644316 |
| Secretory Granule Membrane | GO Cellular Component |
GO:0030667
|
0.29534071 | 4.725659472 | 7.57342643 |
| Secretory Granule Lumen | GO Cellular Component |
GO:0034774
|
0.309398399 | 4.162751323 | 6.209073486 |
| Collagen-Containing Extracellular Matrix | GO Cellular Component |
GO:0062023
|
0.316487088 | 3.514695341 | 4.732293472 |
| Focal Adhesion | GO Cellular Component |
GO:0005925
|
0.316487088 | 3.384801382 | 4.449820407 |
| Cell-Substrate Junction | GO Cellular Component |
GO:0030055
|
0.316487088 | 3.314720812 | 4.29944584 |
| Endoplasmic Reticulum Membrane | GO Cellular Component |
GO:0005789
|
0.522234371 | 1.598666667 | 1.172838783 |
| Embryonic Cranial Skeleton Morphogenesis | GO Biological Process |
GO:0048701
|
0.013686436 | 237.7619048 | 2335.077289 |
| Positive Regulation Of Cellular Process | GO Biological Process |
GO:0048522
|
0.013686436 | 14.96758759 | 142.0401173 |
| Embryonic Skeletal System Morphogenesis | GO Biological Process |
GO:0048704
|
0.025574923 | 101.8163265 | 841.4142386 |
| Aortic Valve Morphogenesis | GO Biological Process |
GO:0003180
|
0.025574923 | 81.4244898 | 638.4786738 |
| Aortic Valve Development | GO Biological Process |
GO:0003176
|
0.025574923 | 74.98496241 | 576.2409325 |
| Positive Regulation Of Cell Population Proliferation | GO Biological Process |
GO:0008284
|
0.025574923 | 13.57341684 | 103.5741349 |
| Branching Morphogenesis Of An Epithelial Tube | GO Biological Process |
GO:0048754
|
0.025574923 | 71.22857143 | 540.4029686 |
| Positive Regulation Of Epithelial To Mesenchymal Transition | GO Biological Process |
GO:0010718
|
0.025574923 | 63.2984127 | 465.9818988 |
| Positive Regulation Of Transcription By RNA Polymerase II | GO Biological Process |
GO:0045944
|
0.025574923 | 9.281399201 | 68.31631987 |
| Positive Regulation Of Cell Differentiation | GO Biological Process |
GO:0045597
|
0.043212206 | 16.23956044 | 107.0734896 |
| Regulation Of Epithelial To Mesenchymal Transition | GO Biological Process |
GO:0010717
|
0.043212206 | 35.10229277 | 218.7460189 |
| Regulation Of Osteoblast Differentiation | GO Biological Process |
GO:0045667
|
0.043212206 | 34.25301205 | 211.8444939 |
| Positive Regulation Of DNA-templated Transcription | GO Biological Process |
GO:0045893
|
0.043212206 | 6.882802174 | 41.94781189 |
| Regulation Of Phosphatidylinositol 3-Kinase Signaling | GO Biological Process |
GO:0014066
|
0.043212206 | 32.2987013 | 196.1192659 |
| Cellular Response To Transforming Growth Factor Beta Stimulus | GO Biological Process |
GO:0071560
|
0.043212206 | 30.22796353 | 179.7071713 |
| Regulation Of Cell Population Proliferation | GO Biological Process |
GO:0042127
|
0.043212206 | 8.408573928 | 49.77054561 |
| Positive Regulation Of Macromolecule Metabolic Process | GO Biological Process |
GO:0010604
|
0.043212206 | 12.5440017 | 73.70179066 |
| Positive Regulation Of Vasculature Development | GO Biological Process |
GO:1904018
|
0.043212206 | 27.84593838 | 161.1693642 |
| Positive Regulation Of Multicellular Organismal Process | GO Biological Process |
GO:0051240
|
0.043212206 | 11.77884615 | 67.16767079 |
| Positive Regulation Of Angiogenesis | GO Biological Process |
GO:0045766
|
0.043212206 | 24.25763126 | 134.0037919 |
Host ncRNA KEGG Pathway Enrichment
| Pathways | Category | Adjusted P-value | Odds Ratio | Combined Score |
|---|---|---|---|---|
| Hippo signaling pathway | KEGG Pathway | 0.000401488 | 41.56184486 | 492.3285315 |
| Gastric cancer | KEGG Pathway | 0.005917416 | 31.35616438 | 265.337742 |
| Proteoglycans in cancer | KEGG Pathway | 0.010052719 | 22.59939071 | 170.0977398 |
| Signaling pathways regulating pluripotency of stem cells | KEGG Pathway | 0.064425496 | 20.10435664 | 103.8691246 |
| Breast cancer | KEGG Pathway | 0.064425496 | 19.54581281 | 99.93758511 |
| Hepatocellular carcinoma | KEGG Pathway | 0.064425496 | 17.05507745 | 82.79971135 |
| Pathways in cancer | KEGG Pathway | 0.064425496 | 8.503496503 | 41.00120166 |
| Diabetic cardiomyopathy | KEGG Pathway | 0.078419119 | 14.06041222 | 63.15371475 |
| Fatty acid biosynthesis | KEGG Pathway | 0.089030112 | 78.30196078 | 332.5412032 |
| MAPK signaling pathway | KEGG Pathway | 0.126337869 | 9.634050881 | 36.52810175 |
| PI3K-Akt signaling pathway | KEGG Pathway | 0.15587426 | 7.967532468 | 27.46687831 |
| Alzheimer disease | KEGG Pathway | 0.15587426 | 7.636045154 | 25.74248073 |
| Proteasome | KEGG Pathway | 0.15587426 | 29.53925926 | 98.04399035 |
| Mineral absorption | KEGG Pathway | 0.165532753 | 22.51412429 | 68.86238459 |
| Basal cell carcinoma | KEGG Pathway | 0.165532753 | 21.42150538 | 64.49927725 |
| Pathways of neurodegeneration | KEGG Pathway | 0.165532753 | 5.892781637 | 17.17467724 |
| Adherens junction | KEGG Pathway | 0.165532753 | 18.96571429 | 54.89429253 |
| Melanoma | KEGG Pathway | 0.165532753 | 18.69765258 | 53.86387318 |
| Chronic myeloid leukemia | KEGG Pathway | 0.165532753 | 17.69688889 | 50.05044052 |
| Pancreatic cancer | KEGG Pathway | 0.165532753 | 17.69688889 | 50.05044052 |
Virus RNA Sequence Information
|
>NC_004102.1 Hepatitis C virus genotype 1, complete genome
GCCAGCCCCCTGATGGGGGCGACACTCCACCATGAATCACTCCCCTGTGAGGAACTACTGTCTTCACGCA
GAAAGCGTCTAGCCATGGCGTTAGTATGAGTGTCGTGCAGCCTCCAGGACCCCCCCTCCCGGGAGAGCCA
TAGTGGTCTGCGGAACCGGTGAGTACACCGGAATTGCCAGGACGACCGGGTCCTTTCTTGGATAAACCCG
CTCAATGCCTGGAGATTTGGGCGTGCCCCCGCAAGACTGCTAGCCGAGTAGTGTTGGGTCGCGAAAGGCC
TTGTGGTACTGCCTGATAGGGTGCTTGCGAGTGCCCCGGGAGGTCTCGTAGACCGTGCACCATGAGCACG
AATCCTAAACCTCAAAGAAAAACCAAACGTAACACCAACCGTCGCCCACAGGACGTCAAGTTCCCGGGTG
GCGGTCAGATCGTTGGTGGAGTTTACTTGTTGCCGCGCAGGGGCCCTAGATTGGGTGTGCGCGCGACGAG
GAAGACTTCCGAGCGGTCGCAACCTCGAGGTAGACGTCAGCCTATCCCCAAGGCACGTCGGCCCGAGGGC
AGGACCTGGGCTCAGCCCGGGTACCCTTGGCCCCTCTATGGCAATGAGGGTTGCGGGTGGGCGGGATGGC
TCCTGTCTCCCCGTGGCTCTCGGCCTAGCTGGGGCCCCACAGACCCCCGGCGTAGGTCGCGCAATTTGGG
TAAGGTCATCGATACCCTTACGTGCGGCTTCGCCGACCTCATGGGGTACATACCGCTCGTCGGCGCCCCT
CTTGGAGGCGCTGCCAGGGCCCTGGCGCATGGCGTCCGGGTTCTGGAAGACGGCGTGAACTATGCAACAG
GGAACCTTCCTGGTTGCTCTTTCTCTATCTTCCTTCTGGCCCTGCTCTCTTGCCTGACTGTGCCCGCTTC
AGCCTACCAAGTGCGCAATTCCTCGGGGCTTTACCATGTCACCAATGATTGCCCTAACTCGAGTATTGTG
TACGAGGCGGCCGATGCCATCCTGCACACTCCGGGGTGTGTCCCTTGCGTTCGCGAGGGTAACGCCTCGA
GGTGTTGGGTGGCGGTGACCCCCACGGTGGCCACCAGGGACGGCAAACTCCCCACAACGCAGCTTCGACG
TCATATCGATCTGCTTGTCGGGAGCGCCACCCTCTGCTCGGCCCTCTACGTGGGGGACCTGTGCGGGTCT
GTCTTTCTTGTTGGTCAACTGTTTACCTTCTCTCCCAGGCGCCACTGGACGACGCAAGACTGCAATTGTT
CTATCTATCCCGGCCATATAACGGGTCATCGCATGGCATGGGATATGATGATGAACTGGTCCCCTACGGC
AGCGTTGGTGGTAGCTCAGCTGCTCCGGATCCCACAAGCCATCATGGACATGATCGCTGGTGCTCACTGG
GGAGTCCTGGCGGGCATAGCGTATTTCTCCATGGTGGGGAACTGGGCGAAGGTCCTGGTAGTGCTGCTGC
TATTTGCCGGCGTCGACGCGGAAACCCACGTCACCGGGGGAAGTGCCGGCCGCACCACGGCTGGGCTTGT
TGGTCTCCTTACACCAGGCGCCAAGCAGAACATCCAACTGATCAACACCAACGGCAGTTGGCACATCAAT
AGCACGGCCTTGAACTGCAATGAAAGCCTTAACACCGGCTGGTTAGCAGGGCTCTTCTATCAGCACAAAT
TCAACTCTTCAGGCTGTCCTGAGAGGTTGGCCAGCTGCCGACGCCTTACCGATTTTGCCCAGGGCTGGGG
TCCTATCAGTTATGCCAACGGAAGCGGCCTCGACGAACGCCCCTACTGCTGGCACTACCCTCCAAGACCT
TGTGGCATTGTGCCCGCAAAGAGCGTGTGTGGCCCGGTATATTGCTTCACTCCCAGCCCCGTGGTGGTGG
GAACGACCGACAGGTCGGGCGCGCCTACCTACAGCTGGGGTGCAAATGATACGGATGTCTTCGTCCTTAA
CAACACCAGGCCACCGCTGGGCAATTGGTTCGGTTGTACCTGGATGAACTCAACTGGATTCACCAAAGTG
TGCGGAGCGCCCCCTTGTGTCATCGGAGGGGTGGGCAACAACACCTTGCTCTGCCCCACTGATTGTTTCC
GCAAGCATCCGGAAGCCACATACTCTCGGTGCGGCTCCGGTCCCTGGATTACACCCAGGTGCATGGTCGA
CTACCCGTATAGGCTTTGGCACTATCCTTGTACCATCAATTACACCATATTCAAAGTCAGGATGTACGTG
GGAGGGGTCGAGCACAGGCTGGAAGCGGCCTGCAACTGGACGCGGGGCGAACGCTGTGATCTGGAAGACA
GGGACAGGTCCGAGCTCAGCCCATTGCTGCTGTCCACCACACAGTGGCAGGTCCTTCCGTGTTCTTTCAC
GACCCTGCCAGCCTTGTCCACCGGCCTCATCCACCTCCACCAGAACATTGTGGACGTGCAGTACTTGTAC
GGGGTAGGGTCAAGCATCGCGTCCTGGGCCATTAAGTGGGAGTACGTCGTTCTCCTGTTCCTCCTGCTTG
CAGACGCGCGCGTCTGCTCCTGCTTGTGGATGATGTTACTCATATCCCAAGCGGAGGCGGCTTTGGAGAA
CCTCGTAATACTCAATGCAGCATCCCTGGCCGGGACGCACGGTCTTGTGTCCTTCCTCGTGTTCTTCTGC
TTTGCGTGGTATCTGAAGGGTAGGTGGGTGCCCGGAGCGGTCTACGCCTTCTACGGGATGTGGCCTCTCC
TCCTGCTCCTGCTGGCGTTGCCTCAGCGGGCATACGCACTGGACACGGAGGTGGCCGCGTCGTGTGGCGG
CGTTGTTCTTGTCGGGTTAATGGCGCTGACTCTGTCGCCATATTACAAGCGCTACATCAGCTGGTGCATG
TGGTGGCTTCAGTATTTTCTGACCAGAGTAGAAGCGCAACTGCACGTGTGGGTTCCCCCCCTCAACGTCC
GGGGGGGGCGCGATGCCGTCATCTTACTCATGTGTGTTGTACACCCGACTCTGGTATTTGACATCACCAA
ACTACTCCTGGCCATCTTCGGACCCCTTTGGATTCTTCAAGCCAGTTTGCTTAAAGTCCCCTACTTCGTG
CGCGTTCAAGGCCTTCTCCGGATCTGCGCGCTAGCGCGGAAGATAGCCGGAGGTCATTACGTGCAAATGG
CCATCATCAAGTTAGGGGCGCTTACTGGCACCTATGTGTATAACCATCTCACCCCTCTTCGAGACTGGGC
GCACAACGGCCTGCGAGATCTGGCCGTGGCTGTGGAACCAGTCGTCTTCTCCCGAATGGAGACCAAGCTC
ATCACGTGGGGGGCAGATACCGCCGCGTGCGGTGACATCATCAACGGCTTGCCCGTCTCTGCCCGTAGGG
GCCAGGAGATACTGCTTGGGCCAGCCGACGGAATGGTCTCCAAGGGGTGGAGGTTGCTGGCGCCCATCAC
GGCGTACGCCCAGCAGACGAGAGGCCTCCTAGGGTGTATAATCACCAGCCTGACTGGCCGGGACAAAAAC
CAAGTGGAGGGTGAGGTCCAGATCGTGTCAACTGCTACCCAAACCTTCCTGGCAACGTGCATCAATGGGG
TATGCTGGACTGTCTACCACGGGGCCGGAACGAGGACCATCGCATCACCCAAGGGTCCTGTCATCCAGAT
GTATACCAATGTGGACCAAGACCTTGTGGGCTGGCCCGCTCCTCAAGGTTCCCGCTCATTGACACCCTGC
ACCTGCGGCTCCTCGGACCTTTACCTGGTCACGAGGCACGCCGATGTCATTCCCGTGCGCCGGCGAGGTG
ATAGCAGGGGTAGCCTGCTTTCGCCCCGGCCCATTTCCTACTTGAAAGGCTCCTCGGGGGGTCCGCTGTT
GTGCCCCGCGGGACACGCCGTGGGCCTATTCAGGGCCGCGGTGTGCACCCGTGGAGTGGCTAAGGCGGTG
GACTTTATCCCTGTGGAGAACCTAGAGACAACCATGAGATCCCCGGTGTTCACGGACAACTCCTCTCCAC
CAGCAGTGCCCCAGAGCTTCCAGGTGGCCCACCTGCATGCTCCCACCGGCAGCGGTAAGAGCACCAAGGT
CCCGGCTGCGTACGCAGCCCAGGGCTACAAGGTGTTGGTGCTCAACCCCTCTGTTGCTGCAACGCTGGGC
TTTGGTGCTTACATGTCCAAGGCCCATGGGGTTGATCCTAATATCAGGACCGGGGTGAGAACAATTACCA
CTGGCAGCCCCATCACGTACTCCACCTACGGCAAGTTCCTTGCCGACGGCGGGTGCTCAGGAGGTGCTTA
TGACATAATAATTTGTGACGAGTGCCACTCCACGGATGCCACATCCATCTTGGGCATCGGCACTGTCCTT
GACCAAGCAGAGACTGCGGGGGCGAGACTGGTTGTGCTCGCCACTGCTACCCCTCCGGGCTCCGTCACTG
TGTCCCATCCTAACATCGAGGAGGTTGCTCTGTCCACCACCGGAGAGATCCCTTTTTACGGCAAGGCTAT
CCCCCTCGAGGTGATCAAGGGGGGAAGACATCTCATCTTCTGCCACTCAAAGAAGAAGTGCGACGAGCTC
GCCGCGAAGCTGGTCGCATTGGGCATCAATGCCGTGGCCTACTACCGCGGTCTTGACGTGTCTGTCATCC
CGACCAGCGGCGATGTTGTCGTCGTGTCGACCGATGCTCTCATGACTGGCTTTACCGGCGACTTCGACTC
TGTGATAGACTGCAACACGTGTGTCACTCAGACAGTCGATTTCAGCCTTGACCCTACCTTTACCATTGAG
ACAACCACGCTCCCCCAGGATGCTGTCTCCAGGACTCAACGCCGGGGCAGGACTGGCAGGGGGAAGCCAG
GCATCTACAGATTTGTGGCACCGGGGGAGCGCCCCTCCGGCATGTTCGACTCGTCCGTCCTCTGTGAGTG
CTATGACGCGGGCTGTGCTTGGTATGAGCTCACGCCCGCCGAGACTACAGTTAGGCTACGAGCGTACATG
AACACCCCGGGGCTTCCCGTGTGCCAGGACCATCTTGAATTTTGGGAGGGCGTCTTTACGGGCCTCACTC
ATATAGATGCCCACTTTCTATCCCAGACAAAGCAGAGTGGGGAGAACTTTCCTTACCTGGTAGCGTACCA
AGCCACCGTGTGCGCTAGGGCTCAAGCCCCTCCCCCATCGTGGGACCAGATGTGGAAGTGTTTGATCCGC
CTTAAACCCACCCTCCATGGGCCAACACCCCTGCTATACAGACTGGGCGCTGTTCAGAATGAAGTCACCC
TGACGCACCCAATCACCAAATACATCATGACATGCATGTCGGCCGACCTGGAGGTCGTCACGAGCACCTG
GGTGCTCGTTGGCGGCGTCCTGGCTGCTCTGGCCGCGTATTGCCTGTCAACAGGCTGCGTGGTCATAGTG
GGCAGGATTGTCTTGTCCGGGAAGCCGGCAATTATACCTGACAGGGAGGTTCTCTACCAGGAGTTCGATG
AGATGGAAGAGTGCTCTCAGCACTTACCGTACATCGAGCAAGGGATGATGCTCGCTGAGCAGTTCAAGCA
GAAGGCCCTCGGCCTCCTGCAGACCGCGTCCCGCCAAGCAGAGGTTATCACCCCTGCTGTCCAGACCAAC
TGGCAGAAACTCGAGGTCTTCTGGGCGAAGCACATGTGGAATTTCATCAGTGGGATACAATACTTGGCGG
GCCTGTCAACGCTGCCTGGTAACCCCGCCATTGCTTCATTGATGGCTTTTACAGCTGCCGTCACCAGCCC
ACTAACCACTGGCCAAACCCTCCTCTTCAACATATTGGGGGGGTGGGTGGCTGCCCAGCTCGCCGCCCCC
GGTGCCGCTACCGCCTTTGTGGGCGCTGGCTTAGCTGGCGCCGCCATCGGCAGCGTTGGACTGGGGAAGG
TCCTCGTGGACATTCTTGCAGGGTATGGCGCGGGCGTGGCGGGAGCTCTTGTAGCATTCAAGATCATGAG
CGGTGAGGTCCCCTCCACGGAGGACCTGGTCAATCTGCTGCCCGCCATCCTCTCGCCTGGAGCCCTTGTA
GTCGGTGTGGTCTGCGCAGCAATACTGCGCCGGCACGTTGGCCCGGGCGAGGGGGCAGTGCAATGGATGA
ACCGGCTAATAGCCTTCGCCTCCCGGGGGAACCATGTTTCCCCCACGCACTACGTGCCGGAGAGCGATGC
AGCCGCCCGCGTCACTGCCATACTCAGCAGCCTCACTGTAACCCAGCTCCTGAGGCGACTGCATCAGTGG
ATAAGCTCGGAGTGTACCACTCCATGCTCCGGTTCCTGGCTAAGGGACATCTGGGACTGGATATGCGAGG
TGCTGAGCGACTTTAAGACCTGGCTGAAAGCCAAGCTCATGCCACAACTGCCTGGGATTCCCTTTGTGTC
CTGCCAGCGCGGGTATAGGGGGGTCTGGCGAGGAGACGGCATTATGCACACTCGCTGCCACTGTGGAGCT
GAGATCACTGGACATGTCAAAAACGGGACGATGAGGATCGTCGGTCCTAGGACCTGCAGGAACATGTGGA
GTGGGACGTTCCCCATTAACGCCTACACCACGGGCCCCTGTACTCCCCTTCCTGCGCCGAACTATAAGTT
CGCGCTGTGGAGGGTGTCTGCAGAGGAATACGTGGAGATAAGGCGGGTGGGGGACTTCCACTACGTATCG
GGTATGACTACTGACAATCTTAAATGCCCGTGCCAGATCCCATCGCCCGAATTTTTCACAGAATTGGACG
GGGTGCGCCTACATAGGTTTGCGCCCCCTTGCAAGCCCTTGCTGCGGGAGGAGGTATCATTCAGAGTAGG
ACTCCACGAGTACCCGGTGGGGTCGCAATTACCTTGCGAGCCCGAACCGGACGTAGCCGTGTTGACGTCC
ATGCTCACTGATCCCTCCCATATAACAGCAGAGGCGGCCGGGAGAAGGTTGGCGAGAGGGTCACCCCCTT
CTATGGCCAGCTCCTCGGCCAGCCAGCTGTCCGCTCCATCTCTCAAGGCAACTTGCACCGCCAACCATGA
CTCCCCTGACGCCGAGCTCATAGAGGCTAACCTCCTGTGGAGGCAGGAGATGGGCGGCAACATCACCAGG
GTTGAGTCAGAGAACAAAGTGGTGATTCTGGACTCCTTCGATCCGCTTGTGGCAGAGGAGGATGAGCGGG
AGGTCTCCGTACCCGCAGAAATTCTGCGGAAGTCTCGGAGATTCGCCCGGGCCCTGCCCGTTTGGGCGCG
GCCGGACTACAACCCCCCGCTAGTAGAGACGTGGAAAAAGCCTGACTACGAACCACCTGTGGTCCATGGC
TGCCCGCTACCACCTCCACGGTCCCCTCCTGTGCCTCCGCCTCGGAAAAAGCGTACGGTGGTCCTCACCG
AATCAACCCTATCTACTGCCTTGGCCGAGCTTGCCACCAAAAGTTTTGGCAGCTCCTCAACTTCCGGCAT
TACGGGCGACAATACGACAACATCCTCTGAGCCCGCCCCTTCTGGCTGCCCCCCCGACTCCGACGTTGAG
TCCTATTCTTCCATGCCCCCCCTGGAGGGGGAGCCTGGGGATCCGGATCTCAGCGACGGGTCATGGTCGA
CGGTCAGTAGTGGGGCCGACACGGAAGATGTCGTGTGCTGCTCAATGTCTTATTCCTGGACAGGCGCACT
CGTCACCCCGTGCGCTGCGGAAGAACAAAAACTGCCCATCAACGCACTGAGCAACTCGTTGCTACGCCAT
CACAATCTGGTGTATTCCACCACTTCACGCAGTGCTTGCCAAAGGCAGAAGAAAGTCACATTTGACAGAC
TGCAAGTTCTGGACAGCCATTACCAGGACGTGCTCAAGGAGGTCAAAGCAGCGGCGTCAAAAGTGAAGGC
TAACTTGCTATCCGTAGAGGAAGCTTGCAGCCTGACGCCCCCACATTCAGCCAAATCCAAGTTTGGCTAT
GGGGCAAAAGACGTCCGTTGCCATGCCAGAAAGGCCGTAGCCCACATCAACTCCGTGTGGAAAGACCTTC
TGGAAGACAGTGTAACACCAATAGACACTACCATCATGGCCAAGAACGAGGTTTTCTGCGTTCAGCCTGA
GAAGGGGGGTCGTAAGCCAGCTCGTCTCATCGTGTTCCCCGACCTGGGCGTGCGCGTGTGCGAGAAGATG
GCCCTGTACGACGTGGTTAGCAAGCTCCCCCTGGCCGTGATGGGAAGCTCCTACGGATTCCAATACTCAC
CAGGACAGCGGGTTGAATTCCTCGTGCAAGCGTGGAAGTCCAAGAAGACCCCGATGGGGTTCTCGTATGA
TACCCGCTGTTTTGACTCCACAGTCACTGAGAGCGACATCCGTACGGAGGAGGCAATTTACCAATGTTGT
GACCTGGACCCCCAAGCCCGCGTGGCCATCAAGTCCCTCACTGAGAGGCTTTATGTTGGGGGCCCTCTTA
CCAATTCAAGGGGGGAAAACTGCGGCTACCGCAGGTGCCGCGCGAGCGGCGTACTGACAACTAGCTGTGG
TAACACCCTCACTTGCTACATCAAGGCCCGGGCAGCCTGTCGAGCCGCAGGGCTCCAGGACTGCACCATG
CTCGTGTGTGGCGACGACTTAGTCGTTATCTGTGAAAGTGCGGGGGTCCAGGAGGACGCGGCGAGCCTGA
GAGCCTTCACGGAGGCTATGACCAGGTACTCCGCCCCCCCCGGGGACCCCCCACAACCAGAATACGACTT
GGAGCTTATAACATCATGCTCCTCCAACGTGTCAGTCGCCCACGACGGCGCTGGAAAGAGGGTCTACTAC
CTTACCCGTGACCCTACAACCCCCCTCGCGAGAGCCGCGTGGGAGACAGCAAGACACACTCCAGTCAATT
CCTGGCTAGGCAACATAATCATGTTTGCCCCCACACTGTGGGCGAGGATGATACTGATGACCCATTTCTT
TAGCGTCCTCATAGCCAGGGATCAGCTTGAACAGGCTCTTAACTGTGAGATCTACGGAGCCTGCTACTCC
ATAGAACCACTGGATCTACCTCCAATCATTCAAAGACTCCATGGCCTCAGCGCATTTTCACTCCACAGTT
ACTCTCCAGGTGAAATCAATAGGGTGGCCGCATGCCTCAGAAAACTTGGGGTCCCGCCCTTGCGAGCTTG
GAGACACCGGGCCCGGAGCGTCCGCGCTAGGCTTCTGTCCAGAGGAGGCAGGGCTGCCATATGTGGCAAG
TACCTCTTCAACTGGGCAGTAAGAACAAAGCTCAAACTCACTCCAATAGCGGCCGCTGGCCGGCTGGACT
TGTCCGGTTGGTTCACGGCTGGCTACAGCGGGGGAGACATTTATCACAGCGTGTCTCATGCCCGGCCCCG
CTGGTTCTGGTTTTGCCTACTCCTGCTCGCTGCAGGGGTAGGCATCTACCTCCTCCCCAACCGATGAAGG
TTGGGGTAAACACTCCGGCCTCTTAGGCCATTTCCTGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTCTTTTTTTTTTTTTTTTTCCTTTTTTTTTTTTTTTTTTTTCTTTCCTTCTTT
TTTCCTTTCTTTTCCTTCCTTCTTTAATGGTGGCTCCATCTTAGCCCTAGTCACGGCTAGCTGTGAAAGG
TCCGTGAGCCGCATGACTGCAGAGAGTGCTGATACTGGCCTCTCTGCAGATCATGT
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