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DownloadHost Protein General Information
| Protein Name |
Poly(rC)-binding protein 2
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Gene Name |
PCBP2
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| Host Species |
Homo sapiens
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Uniprot Entry Name |
PCBP2_HUMAN
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| Subcellular Location |
Nucleus
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| External Link | |||||||||
| NCBI Gene ID | |||||||||
| Uniprot ID | |||||||||
| Ensembl ID | |||||||||
| HGNC ID | |||||||||
| Related KEGG Pathway | |||||||||
| Ferroptosis | hsa04216 |
Pathway Map 
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| 3D Structure |
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Full List of Virus RNA Interacting with This Protien
| Virus Name | Binding Region | RNA Info | Detection Method | Infection Cell | Cell ID | Cell Originated Tissue | Infection Time | Interaction Score 1 | Interaction Score 2 |
|---|---|---|---|---|---|---|---|---|---|
| Poliovirus | 5'UTR - stem lops | RNA Info | RNA footprinting (RNA FP) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Poliovirus | 5'UTR | RNA Info | UV cross-linking (UVX) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Poliovirus | 5'UTR - 3'UTR | RNA Info | Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and western blotting with anti-PCBP polyclonal anti serum | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 7 h | . | . |
| Poliovirus | 5'UTR - 3'UTR | RNA Info | Electrophoretic mobility shift assay (EMSA) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Hepatitis C virus | 5'UTR | RNA Info | Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) | HuH-7 Cells (Human hepatocellular carcinoma cell) | . | Liver | . | . | . |
| Poliovirus | 5'UTR - 3'UTR | RNA Info | Thiouracil cross-linking mass spectrometry (TUX-MS) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | 5 h | . | . |
| Sindbis virus | 5'UTR - 3'UTR | RNA Info | comparative RIC | HEK293 Cells (Human embryonic kidney cell); Mesc cells (Embryonic stem cell) | . | Kidney | 18 h | MIST = 0.671261317 | . |
| Dengue virus | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) | . | Liver | 48 h | . | . |
| Zika virus | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) | . | Liver | 48 h | . | . |
| Dengue virus 2 | 3'UTR | RNA Info | Protein-RNA reconstitution and a stringent RNA pulldown assay | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Encephalomyocarditis virus | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5 Cells (Human hepatocellular carcinoma cell) | . | Liver | . | Z-score = -11.50463917 | FZR = 1.26261E-27 |
| Influenza A virus | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5 Cells (Human hepatocellular carcinoma cell) | . | Liver | . | Z-score = -8.238248925 | FZR = 2.18E-13 |
| Poliovirus | 5'UTR - stem lops | RNA Info | RNA electrophoretic mobility shift assays (RNA EMSA) | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Zika virus (strain PRVABC59) | 3'UTR | RNA Info | Protein-RNA reconstitution and a stringent RNA pulldown assay | HeLa Cells (Human cervical carcinoma cell) | . | Cervix | . | . | . |
| Hepatitis C virus (strain JFH-1) | 3'UTR | RNA Info | Crosslinking with immunoprecipitation followed by sequencing (CLIP-seq) | HuH-7 Cells (Human hepatocellular carcinoma cell) | . | Liver | 5 h | . | . |
| Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/USA/WA1/2020) | Not Specified Virus Region | RNA Info | ChIRP-MS | Huh7.5 cells (Hepatocyte derived cellular carcinoma cell) | . | Liver | 48 h | FDR <= 0.05 | . |
| Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/Not Specified Virus Strain) | Not Specified Virus Region | RNA Info | RNAantisensepurificationandquantitativemassspectrometry(RAP-MS); Tandemmasstag(TMT)labelling; liquidchromatographycoupledwithtandemmassspectrometry(LC-MS/MS); Westernblot | Huh7 cells (liver carcinoma celll ine) | . | Liver | 24h | log2 fold change = 1.73028E+14 | . |
| Severe acute respiratory syndrome coronavirus 2 (strain hCoV-19/France/IDF-220-95/2020) | Not Specified Virus Region | RNA Info | ChIRP-M/S | HEK 293T cells stably expressing the human ACE2 receptor (293T-ACE2) | . | Embryonic kidneys | 48 h | SAINT score >= 0.79 | . |
| Dengue virus 2 (strain 16681) | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) | . | Liver | 48 h | Saint score = 1 | MIST = 2.497 |
| Dengue virus 2 (strain 16681) | 5'UTR - 3'UTR | RNA Info | Comprehensive identification of RNA-binding proteins by mass spectrometry (ChIRP-MS) | HuH-7.5.1 Cells (Human hepatocellular carcinoma cell) | . | Liver | 48 h | Saint score = 1 | MIST = 1.613 |
Protein Sequence Information
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MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS
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